Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 10/20 | 0.37 |
| ▸ | ACHE | P22303 | 10/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 3/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6874755 | 0.85 | SIGMAR1 (0.49) | TRPM8HTR1DBCHEACHEMEN1 | |
| SCHEMBL6874760 | 0.85 | SIGMAR1 (0.49) | TRPM8HTR1DBCHEACHEMEN1 | |
| SCHEMBL27652689 | 0.80 | NOX1 (0.39) | BCHEACHEKMT2AADRA2AMCHR1 | |
| SCHEMBL27652688 | 0.80 | NOX1 (0.39) | BCHEACHEKMT2AADRA2AMCHR1 | |
| SCHEMBL6877480 | 0.75 | NOX1 (0.48) | MEN1KMT2ALTA4HADRA2AMCHR1 | |
| SCHEMBL6877475 | 0.75 | NOX1 (0.48) | MEN1KMT2ALTA4HADRA2AMCHR1 | |
| SCHEMBL13793201 | 0.73 | MCHR1 (0.53) | TRPM8HTR1DMEN1KMT2ASLC6A4 | |
| SCHEMBL7046594 | 0.72 | ALDH1A1 (0.50) | ACHEMEN1KMT2AADRA2AMCHR1 | |
| SCHEMBL27653038 | 0.72 | MCHR1 (0.38) | BCHEACHEADRA2AMCHR1 | |
| SCHEMBL27653039 | 0.72 | MCHR1 (0.38) | BCHEACHEADRA2AMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |