Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29687055 | 1.00 | RAB9A (0.58) | RAB9ANPC1MAPTSMN1; SMN2GAA | |
| SCHEMBL19020205 | 0.84 | RAB9A (0.65) | RAB9ANPC1MAPTSMN1; SMN2GAA | |
| SCHEMBL4299166 | 0.81 | RAB9A (0.47) | RAB9ANPC1MAPTSMN1; SMN2GAA | |
| SCHEMBL6873113 | 0.81 | HSD17B10 (0.62) | RAB9ANPC1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL1903330 | 0.81 | HSD17B10 (0.62) | RAB9ANPC1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL29687100 | 0.79 | TSHR (0.76) | RAB9ANPC1MAPTSMN1; SMN2GAA | |
| SCHEMBL9547503 | 0.79 | RAB9A (0.89) | RAB9ANPC1MAPTSMN1; SMN2GAA | |
| SCHEMBL29687046 | 0.78 | KIF11 (0.58) | RAB9ANPC1SMN1; SMN2CA2MEN1 | |
| SCHEMBL29686974 | 0.77 | HTR2C (0.45) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL29687222 | 0.76 | KIF11 (0.51) | RAB9ANPC1MAPTCA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1452522-A2 | Novel compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2004-09-01 | — | — | EP | disclosed |