Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.42 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 14/20 | 0.39 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6873804 | 0.80 | HRH4 (0.43) | HRH4SMYD3PDE10A | |
| SCHEMBL2227969 | 0.73 | HRH4 (0.45) | HRH4SMYD3PDE10ARBP4 | |
| SCHEMBL2227562 | 0.69 | DRD2 (0.42) | HRH4SMYD3PDE10A | |
| SCHEMBL8002379 | 0.69 | GAA (0.40) | SMYD3 | |
| SCHEMBL25877347 | 0.69 | GAA (0.40) | — | |
| SCHEMBL3224952 | 0.68 | HRH4 (0.45) | HRH4SMYD3PDE10ARBP4 | |
| SCHEMBL25664269 | 0.67 | GAA (0.37) | SMYD3 | |
| SCHEMBL7943730 | 0.67 | HRH4 (0.42) | HRH4PDE10A | |
| SCHEMBL6876456 | 0.67 | HRH4 (0.53) | HRH4SMYD3PDE10ARBP4 | |
| SCHEMBL6872087 | 0.66 | HRH4 (0.51) | HRH4PDE10ARBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011091410-A1 | TRPV4 ANTAGONISTS | GLAXOS SMITHKLINE LLC (US) | 2011-07-28 | — | — | WO | disclosed |