Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6879325 | 0.90 | GAA (0.53) | GAAL3MBTL1ALDH1A1NPSR1TSHR | |
| SCHEMBL6876792 | 0.90 | GAA (0.49) | GAAL3MBTL1ALDH1A1NPSR1TSHR | |
| SCHEMBL6878000 | 0.84 | GAA (0.46) | GAAL3MBTL1ALDH1A1NPSR1TSHR | |
| SCHEMBL15840964 | 0.79 | GAA (0.57) | GAAL3MBTL1ALDH1A1NPSR1TSHR | |
| SCHEMBL10309075 | 0.79 | GAA (0.57) | GAAL3MBTL1ALDH1A1NPSR1TSHR | |
| SCHEMBL25211939 | 0.79 | GAA (0.57) | GAAL3MBTL1ALDH1A1NPSR1TSHR | |
| SCHEMBL6187607 | 0.79 | MAPK1 (0.64) | GAAL3MBTL1ALDH1A1NPSR1MAPK1 | |
| SCHEMBL8658204 | 0.78 | MAPK1 (0.62) | GAAL3MBTL1ALDH1A1NPSR1MAPK1 | |
| SCHEMBL9390364 | 0.77 | HPGD (0.51) | GAAL3MBTL1ALDH1A1NPSR1TSHR | |
| SCHEMBL15330130 | 0.77 | GAA (0.54) | GAAL3MBTL1ALDH1A1NPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117126143-A | Method for synthesizing (tetrahydrofuran-2-yl) heteroaromatic compound | 苏州大学 | 2023-11-28 | — | — | CN | disclosed |
| WO-2023019430-A1 | COMPOUNDS AS IMMUNOMODULATORS OF PD-L1 INTERACTIONS | ASCLETIS BIOSCIENCE CO., LTD. (CN) | 2023-02-23 | — | — | WO | disclosed |
| US-9918987-B2 | Substituted xanthine derivatives | CONCERT PHARMACEUTICALS, INC. (US) | 2018-03-20 | — | — | US | disclosed |
| EP-3205652-A1 | HYDROXYL PURINE COMPOUNDS AND APPLICATIONS THEREOF | Medshine Discovery Inc. (CN) | 2017-08-16 | — | — | EP | disclosed |
| US-9688701-B2 | Production and use of zinc amides | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2017-06-27 | — | — | US | disclosed |
| WO-2017071606-A1 | MEDICAL USE OF HYDROXYL PURINE COMPOUND | 南京明德新药研发股份有限公司 | 2017-05-04 | — | — | WO | disclosed |
| US-20160215000-A1 | Production And Use Of Zinc Amides | UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) | 2016-07-28 | — | — | US | disclosed |
| US-20110053961-A1 | SUBSTITUTED XANTHINE DERIVATIVES | CONCERT PHARMACEUTICALS, INC. | 2011-03-03 | — | — | US | disclosed |
| US-7884202-B2 | Nucleobases are perfluoroalkylated in a one step process with a perfluoroalkyl halide in the presence of a sulfoxide, a peroxide and an iron compound; useful as medicinal drugs, intermediates for medicinal drugs and agricultural chemicals | TOSOH CORPORATION (JP) | 2011-02-08 | — | — | US | disclosed |
| US-7772226-B2 | Condensed imidazole derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-08-10 | — | — | US | disclosed |
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |
| US-20090018331-A1 | CONDENSED IMIDAZOLE DERIVATIVES | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-01-15 | — | — | US | disclosed |
| US-20070219178-A1 | PREVENTIVE OR THERAPEUTIC AGENTS FOR MULTIPLE SCLEROSIS | EISAI CO., LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053961-A1 | SUBSTITUTED XANTHINE DERIVATIVES | XDH, HPRT1, CXCR3 | GAA 1144/4885L3MBTL1 2800/4885ALDH1A1 699/4885 |
| US-20070219178-A1 | PREVENTIVE OR THERAPEUTIC AGENTS FOR MULTIPLE SCLEROSIS | MYT1, AQP4, AQP1 | GAA 3389/4885L3MBTL1 1819/4885ALDH1A1 1186/4885 |
| US-20160215000-A1 | Production And Use Of Zinc Amides | SCLY, CBR3, SCO2 | GAA 4798/4885L3MBTL1 1251/4885ALDH1A1 2994/4885 |
| US-20090018331-A1 | CONDENSED IMIDAZOLE DERIVATIVES | DPP4, HDAC1, DPP7 | GAA 3065/4885L3MBTL1 1022/4885ALDH1A1 686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.