Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 12/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 7/20 | 0.48 |
| ▸ | HTR2B | P41595 | 6/20 | 0.48 |
| ▸ | HRH1 | P35367 | 5/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.40 |
| ▸ | MERTK | Q12866 | 1/20 | 0.40 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6464429 | 1.00 | TSHR (0.50) | TSHRALDH1A1MCHR1ADRA2AHTR2B | |
| SCHEMBL6877675 | 0.85 | MCHR1 (0.62) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6875844 | 0.85 | MCHR1 (0.48) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6875836 | 0.85 | MCHR1 (0.48) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6879241 | 0.82 | MCHR1 (0.63) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6879245 | 0.82 | MCHR1 (0.63) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6462936 | 0.81 | ALDH1A1 (0.51) | TSHRALDH1A1MCHR1ADRA2AL3MBTL1 | |
| SCHEMBL6873997 | 0.81 | ALDH1A1 (0.51) | TSHRALDH1A1MCHR1ADRA2AL3MBTL1 | |
| SCHEMBL6875280 | 0.81 | MCHR1 (0.50) | ALDH1A1MCHR1ADRA2AHTR2BHRH1 | |
| SCHEMBL6875273 | 0.81 | MCHR1 (0.50) | ALDH1A1MCHR1ADRA2AHTR2BHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |