Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEH1 | O60930 | 1/20 | 0.40 |
| ▸ | CENPE | Q02224 | 5/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6883233 | 0.91 | ATM (0.39) | ERCC1FEN1ERCC4PIN1 | |
| SCHEMBL6886326 | 0.89 | ERCC1 (0.36) | ERCC1FEN1ERCC4PIN1 | |
| SCHEMBL6883811 | 0.83 | RNASEH1 (0.41) | RNASEH1ADORA2BADORA1PIN1 | |
| SCHEMBL6883448 | 0.79 | RNASEH1 (0.44) | RNASEH1CENPEERCC1FEN1ERCC4 | |
| SCHEMBL6884173 | 0.79 | HTR1A (0.43) | RNASEH1ERCC1FEN1ERCC4PIN1 | |
| SCHEMBL6883024 | 0.79 | RNASEH1 (0.44) | RNASEH1ERCC1FEN1ERCC4ROCK2 | |
| SCHEMBL6885510 | 0.78 | PIN1 (0.54) | RNASEH1ERCC1FEN1ERCC4PIN1 | |
| SCHEMBL6884051 | 0.77 | RNASEH1 (0.46) | RNASEH1CENPEERCC1FEN1ERCC4 | |
| SCHEMBL6885308 | 0.76 | PIN1 (0.38) | RNASEH1PIN1 | |
| SCHEMBL6017817 | 0.76 | RNASEH1 (0.43) | RNASEH1CENPEPIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096128-A2 | HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-11-11 | — | — | WO | claimed |
| WO-2004096128-A2 | HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-11-11 | — | — | WO | disclosed |