SCHEMBL6879879

SCHEMBL6879879

O=C(O)C1C2CC3CC1C(C(=O)O)C(O)(C3)C2

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 5/20 0.35
GRM5 P41594 4/20 0.35
GRM4 Q14833 3/20 0.35
GRM6 O15303 2/20 0.35
GRM1 Q13255 2/20 0.35
GRM3 Q14832 2/20 0.35
GRM8 O00222 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6742682 0.77 THRB (0.36)
SCHEMBL20129585 0.70 GRM5 (0.41) GRM2GRM5GRM4GRM6GRM1
SCHEMBL161518 0.67 THRB (0.38)
SCHEMBL14118138 0.66 POLB (0.39) GRM2GRM5GRM4GRM6GRM1
SCHEMBL7741675 0.65 POLB (0.38) GRM2GRM5GRM4GRM6GRM1
SCHEMBL7734535 0.64 EPHX1 (0.35)
SCHEMBL7965513 0.64 GRM2 (0.40) GRM2GRM5GRM4GRM6GRM1
SCHEMBL26217911 0.64 GRM2 (0.44) GRM2GRM5GRM4GRM6GRM1
SCHEMBL3929216 0.64 ALDH1A1 (0.38)
SCHEMBL7965517 0.64 GRM2 (0.40) GRM2GRM5GRM4GRM6GRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6824957-B2 RESIST COMPOSITION HAVING HIGH TRANSPARENCY AGAINST SHORT-WAVELENGTH LIGHT AND HIGH DRY- ETCHING RESISTANCE, CAPABLE OF FORMING A RESIST PATTERN EXCELLENT IN ADHESION AND RESOLUTION BY MEANS OF ALKALI DEVELOPMENT KABUSHIKI KAISHA TOSHIBA (JP) 2004-11-30 US disclosed