SCHEMBL6880077

SCHEMBL6880077

[c]1ccc(-c2ccc(-c3ccccc3)cc2)c(-c2ccc(-c3ccccc3)cc2)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
HSD17B10 Q99714 3/20 0.37
MAPK1 P28482 2/20 0.37
BCL2L1 Q07817 2/20 0.37
TAAR1 Q96RJ0 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
MMP3 P08254 1/20 0.37
PTGS2 P35354 1/20 0.36
BACE1 P56817 1/20 0.36
HPGD P15428 1/20 0.34
CYP2A6 P11509 1/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
MGLL Q99685 1/20 0.33
KIF11 P52732 1/20 0.33
CASP3 P42574 1/20 0.32
SENP8 Q96LD8 1/20 0.32
SENP7 Q9BQF6 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27629739 1.00 ALDH1A1 (0.41) ALDH1A1HSD17B10MAPK1BCL2L1TAAR1
SCHEMBL445102 1.00 ALDH1A1 (0.41) ALDH1A1HSD17B10MAPK1BCL2L1TAAR1
SCHEMBL618853 0.95 BACE1 (0.39) ALDH1A1HSD17B10MAPK1BCL2L1TDP1
SCHEMBL6474583 0.91 BACE1 (0.36) ALDH1A1HSD17B10MAPK1BCL2L1PTGS2
SCHEMBL3870533 0.91 BACE1 (0.36) ALDH1A1HSD17B10MAPK1BCL2L1PTGS2
SCHEMBL6966765 0.88 MAOA (0.38) ALDH1A1BACE1MGLLMEN1APAF1
SCHEMBL9770283 0.88 PTGS2 (0.41) CYP1A2PTGS2HPGD
SCHEMBL18832483 0.86 ALDH1A1 (0.39) ALDH1A1HSD17B10MAPK1BCL2L1TDP1
SCHEMBL9957984 0.84 NOTUM (0.52) ALDH1A1HSD17B10MAPK1MEN1NPC1
SCHEMBL9958265 0.84 NOTUM (0.52) ALDH1A1HSD17B10MAPK1MEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040260039-A1 Process for producing organic compound epoxy resin composition, cured article obtained from the epoxy resin, and semiconductor device obtained with epoxy resin MITSUI CHEMICALS, INC. (JP) 2004-12-23 US disclosed
EP-0950649-B1 A process for preparing oxyalkylene derivatives in the presence of phosphine oxides MITSUI CHEMICALS INC (JP) 2003-03-26 EP disclosed
US-6130346-A ESTERIFICATION, CARBONATION, SULFONATION, ETHERIFICATION MITSUI CHEMICALS, INC. (JP) 2000-10-10 US disclosed
EP-0950649-A1 A process for preparing oxyalkylene derivatives in the presence of phosphine oxides Mitsui Chemicals, Inc. (JP) 1999-10-20 EP disclosed