SCHEMBL3870533

SCHEMBL3870533

[c]1ccc(-c2cc[c]cc2-c2ccccc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.36
ALDH1A1 P00352 4/20 0.35
HSD17B10 Q99714 2/20 0.34
CYP2A6 P11509 2/20 0.34
HPGD P15428 1/20 0.34
BCL2L1 Q07817 1/20 0.34
MAPK1 P28482 1/20 0.34
NISCH Q9Y2I1 1/20 0.33
PTGS2 P35354 1/20 0.32
ALOX5 P09917 1/20 0.31
DPP4 P27487 1/20 0.31
GPR55 Q9Y2T6 1/20 0.31
HDAC4 P56524 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC8 Q9BY41 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30
CYP2B6 P20813 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6474583 1.00 BACE1 (0.36) BACE1ALDH1A1HSD17B10CYP2A6HPGD
SCHEMBL618853 0.95 BACE1 (0.39) BACE1ALDH1A1HSD17B10CYP2A6HPGD
SCHEMBL445102 0.91 ALDH1A1 (0.41) BACE1ALDH1A1HSD17B10CYP2A6HPGD
SCHEMBL6880077 0.91 ALDH1A1 (0.41) BACE1ALDH1A1HSD17B10CYP2A6HPGD
SCHEMBL27629739 0.91 ALDH1A1 (0.41) BACE1ALDH1A1HSD17B10CYP2A6HPGD
SCHEMBL18832483 0.86 ALDH1A1 (0.39) BACE1ALDH1A1HSD17B10CYP2A6HPGD
SCHEMBL1371612 0.85 ALDH1A1 (0.46) BACE1ALDH1A1HSD17B10CYP2A6HPGD
SCHEMBL9957984 0.84 NOTUM (0.52) ALDH1A1HSD17B10MAPK1
SCHEMBL9770283 0.84 PTGS2 (0.41) HPGDPTGS2
SCHEMBL9958265 0.84 NOTUM (0.52) ALDH1A1HSD17B10MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3294727-B1 ORGANIC LIGHT-EMITTING DIODE COMPRISING DIFFERENT MATRIX COMPOUNDS IN THE FIRST AND SECOND ELECTRON TRANSPORT LAYER NOVALED GMBH (DE) 2021-08-04 EP claimed
US-11081652-B2 Organic light-emitting diode comprising different matrix compounds in the first and second electron transport layer NOVALED GMBH (DE) 2021-08-03 US claimed
CN-107750404-B Organic light emitting diode comprising different host compounds in first and second electron transport layers 诺瓦尔德股份有限公司 2021-06-04 CN claimed
US-20180145263-A1 Organic Light-Emitting Diode Comprising Different Matrix Compounds in the First and Second Electron Transport Layer NOVALED GMBH (DE) 2018-05-24 US claimed
EP-3294727-A1 ORGANIC LIGHT-EMITTING DIODE COMPRISING DIFFERENT MATRIX COMPOUNDS IN THE FIRST AND SECOND ELECTRON TRANSPORT LAYER Novaled GmbH (DE) 2018-03-21 EP claimed
WO-2016180891-A1 ORGANIC LIGHT-EMITTING DIODE COMPRISING DIFFERENT MATRIX COMPOUNDS IN THE FIRST AND SECOND ELECTRON TRANSPORT LAYER NOVALED GMBH (DE) 2016-11-17 WO claimed
EP-3093288-A1 ORGANIC LIGHT-EMITTING DIODE COMPRISING DIFFERENT MATRIX COMPOUNDS IN THE FIRST AND SECOND ELECTRON TRANSPORT LAYER Novaled GmbH (DE) 2016-11-16 EP claimed
US-7482490-B2 Amine compound having fluorene group as framework, process for producing the amine compound, and use of the amine compound TOSOH CORPORATION (JP) 2009-01-27 US claimed
US-20080194878-A1 Amine Compound Having Fluorene Group as Framework, Process for Producing the Amine Compound, and Use of the Amine Compound TOSOH CORPORATION (JP) 2008-08-14 US claimed
EP-1752440-A1 AMINE COMPOUND HAVING FLUORENE GROUP AS FRAMEWORK, PROCESS FOR PRODUCING THE AMINE COMPOUND, AND USE OF THE AMINE COMPOUND Tosoh Corporation (JP) 2007-02-14 EP claimed
CN-117916215-A Indene compound, pharmaceutical composition thereof and therapeutic application thereof 藤济(厦门)生物医药科技有限公司 2024-04-19 CN disclosed
CN-116472034-A Indene compound, pharmaceutical composition thereof and therapeutic application thereof 藤济(厦门)生物医药科技有限公司 2023-07-21 CN disclosed
EP-3294727-B1 ORGANIC LIGHT-EMITTING DIODE COMPRISING DIFFERENT MATRIX COMPOUNDS IN THE FIRST AND SECOND ELECTRON TRANSPORT LAYER NOVALED GMBH (DE) 2021-08-04 EP disclosed
US-11081652-B2 Organic light-emitting diode comprising different matrix compounds in the first and second electron transport layer NOVALED GMBH (DE) 2021-08-03 US disclosed
CN-107750404-B Organic light emitting diode comprising different host compounds in first and second electron transport layers 诺瓦尔德股份有限公司 2021-06-04 CN disclosed
WO-2016180891-A1 ORGANIC LIGHT-EMITTING DIODE COMPRISING DIFFERENT MATRIX COMPOUNDS IN THE FIRST AND SECOND ELECTRON TRANSPORT LAYER NOVALED GMBH (DE) 2016-11-17 WO disclosed
EP-3093288-A1 ORGANIC LIGHT-EMITTING DIODE COMPRISING DIFFERENT MATRIX COMPOUNDS IN THE FIRST AND SECOND ELECTRON TRANSPORT LAYER Novaled GmbH (DE) 2016-11-16 EP disclosed
US-7482490-B2 Amine compound having fluorene group as framework, process for producing the amine compound, and use of the amine compound TOSOH CORPORATION (JP) 2009-01-27 US disclosed
US-20080194878-A1 Amine Compound Having Fluorene Group as Framework, Process for Producing the Amine Compound, and Use of the Amine Compound TOSOH CORPORATION (JP) 2008-08-14 US disclosed
EP-1752440-A1 AMINE COMPOUND HAVING FLUORENE GROUP AS FRAMEWORK, PROCESS FOR PRODUCING THE AMINE COMPOUND, AND USE OF THE AMINE COMPOUND Tosoh Corporation (JP) 2007-02-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11081652-B2 Organic light-emitting diode comprising different matrix compounds in the first and second electron transport layer CYBA, CLTB, MAP1LC3B BACE1 3119/4885ALDH1A1 122/4885HSD17B10 442/4885
US-20080194878-A1 Amine Compound Having Fluorene Group as Framework, Process for Producing the Amine Compound, and Use of the Amine Compound TAAR1, SLC18A1, ADRB2 BACE1 3921/4885ALDH1A1 1351/4885HSD17B10 1406/4885
US-20180145263-A1 Organic Light-Emitting Diode Comprising Different Matrix Compounds in the First and Second Electron Transport Layer CYBA, CLTB, MAP1LC3B BACE1 3119/4885ALDH1A1 122/4885HSD17B10 442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.