Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688777 | 0.82 | GPR35 (0.51) | ALDH1A1KMT2AAKR1B1RAB9ASMN1; SMN2 | |
| SCHEMBL11607651 | 0.81 | ALDH1A1 (0.71) | ALDH1A1KMT2ASMN1; SMN2MAPTPKM | |
| SCHEMBL689127 | 0.81 | GPR35 (0.50) | ALDH1A1KMT2AAKR1B1RAB9ASMN1; SMN2 | |
| SCHEMBL4360014 | 0.80 | PKM (0.57) | ALDH1A1KMT2ARAB9ASMN1; SMN2MITF | |
| SCHEMBL4360020 | 0.80 | PKM (0.57) | ALDH1A1KMT2ARAB9ASMN1; SMN2MITF | |
| SCHEMBL11445926 | 0.80 | ALDH1A1 (0.56) | ALDH1A1KMT2ASMN1; SMN2MAPTATM | |
| SCHEMBL30629527 | 0.80 | ALDH1A1 (0.56) | ALDH1A1KMT2ASMN1; SMN2MAPTATM | |
| SCHEMBL688882 | 0.80 | MAPT (0.57) | ALDH1A1KMT2ASMN1; SMN2MAPTGPR35 | |
| SCHEMBL689300 | 0.80 | GPR35 (0.49) | ALDH1A1KMT2AAKR1B1RAB9ASMN1; SMN2 | |
| SCHEMBL30311924 | 0.80 | GPR35 (0.49) | ALDH1A1KMT2AAKR1B1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160100-A | OXAMIC ACID DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1979-07-03 | — | — | US | claimed |
| EP-1953148-B1 | HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2012-02-29 | — | — | EP | disclosed |
| US-7915267-B2 | Heterocyclic amide compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-03-29 | — | — | US | disclosed |
| US-4195025-A | 9-Amino-dibenzopyrans | ELI LILLY AND COMPANY (US) | 1980-03-25 | — | — | US | disclosed |
| US-4191840-A | Oxamic acid derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-03-04 | — | — | US | disclosed |
| EP-0003883-A1 | Amino-dibenzopyrans, their preparation, formulations containing them and their use as pharmaceuticals | ELI LILLY AND COMPANY (US) | 1979-09-05 | — | — | EP | disclosed |
| US-4160100-A | OXAMIC ACID DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1979-07-03 | — | — | US | disclosed |
| US-4154961-A | Oxamic acid derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1979-05-15 | — | — | US | disclosed |
| US-4152450-A | 9-Amino-dibenzopyrans | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | disclosed |
| US-4069343-A | OXAMIC ACID DERIVATIVES FOR THE PREVENTION OF IMMEDIATE TYPE HYPERSENSITIVITY REACTIONS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-01-17 | — | — | US | disclosed |
| US-4054666-A | Compositions and methods of treating immediate hypersensitivity reactions with thiazolyl oxamic acid derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-10-18 | — | — | US | disclosed |
| US-4054661-A | Pyridyl oxamic acid derivatives and use in the prevention of allergic reactions | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-10-18 | — | — | US | disclosed |
| US-4054657-A | Pyrimidinyl oxamic acids and esters, and compositions and methods for the suppression of allergic manifestations | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-10-18 | — | — | US | disclosed |
| US-4036837-A | 2 Alkoxyoxamoyl-pyrazines | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-07-19 | — | — | US | disclosed |
| US-3966965-A | Oxamic acid derivatives for the prevention of immediate type hypersensitivity reactions | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-06-29 | — | — | US | disclosed |