Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.49 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 6/20 | 0.46 |
| ▸ | KDR | P35968 | 6/20 | 0.46 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.41 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | BRS3 | P32247 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6881176 | 0.83 | TAAR1 (0.43) | — | |
| SCHEMBL6882204 | 0.82 | SCN2A (0.46) | MEN1NPC1MAPTRAB9AKMT2A | |
| SCHEMBL6236885 | 0.75 | CDC7 (0.55) | CDC7ALKCDK1KDRMAPKAPK2 | |
| SCHEMBL9844921 | 0.69 | TDP1 (0.62) | CDC7ALKCDK1KDRMAPKAPK2 | |
| SCHEMBL6881611 | 0.66 | CDC7 (0.40) | CDC7ALKCDK1KDRMAPKAPK2 | |
| SCHEMBL7169361 | 0.65 | CA2 (0.56) | CDC7ALKCDK1KDRMAPKAPK2 | |
| SCHEMBL1938644 | 0.64 | TDP1 (0.71) | MAPKAPK2TDP1LMNARAB9A | |
| SCHEMBL22251662 | 0.64 | TDP1 (0.71) | MAPKAPK2TDP1LMNARAB9A | |
| SCHEMBL15380931 | 0.64 | MEN1 (0.42) | CDK1KDRMEN1NPC1MAPT | |
| SCHEMBL9603150 | 0.61 | HDAC3 (0.67) | LMNAMAPTKMT2ANPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832091-B1 | C-4' MODIFIED ADENOSINE KINASE INHIBITORS | GENSIA SICOR INC (US) | 2004-01-14 | — | — | EP | disclosed |