Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN2A | Q99250 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6881176 | 0.80 | TAAR1 (0.43) | CYP1A2CYP3A4 | |
| SCHEMBL6683647 | 0.72 | PDE5A (0.41) | SCN2AMEN1KMT2AGSK3AGSK3B | |
| SCHEMBL15380931 | 0.67 | MEN1 (0.42) | SCN2AMEN1KMT2AGSK3BCDK2 | |
| SCHEMBL22182573 | 0.66 | CYP1A2 (0.71) | CYP1A2GSK3BPDE5AABCG2TP53 | |
| SCHEMBL32660979 | 0.65 | FABP3 (0.47) | CYP1A2GSK3AGSK3BPDE5AABCG2 | |
| SCHEMBL27018956 | 0.65 | CYP1A2 (0.46) | MEN1CYP1A2KMT2APDE5AABCG2 | |
| SCHEMBL994128 | 0.64 | MEN1 (0.50) | MEN1KMT2AGSK3BMAPTJAK2 | |
| SCHEMBL27685288 | 0.64 | VCP (0.52) | SCN2AMEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL14040937 | 0.63 | XDH (0.47) | MEN1KMT2AGSK3AGSK3BCDK2 | |
| SCHEMBL25286380 | 0.63 | SCN2A (0.60) | SCN2ACYP1A2CYP3A4CYP2C19GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832091-B1 | C-4' MODIFIED ADENOSINE KINASE INHIBITORS | GENSIA SICOR INC (US) | 2004-01-14 | — | — | EP | disclosed |