Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 2/20 | 0.39 |
| ▸ | EED | O75530 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | BPTF | Q12830 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | LSS | P48449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6881613 | 0.83 | CDC7 (0.49) | — | |
| SCHEMBL6882204 | 0.80 | SCN2A (0.46) | CYP1A2CYP3A4 | |
| SCHEMBL6235340 | 0.76 | ACP1 (0.41) | TAAR1ACP1EEDCHEK1ALDH1A1 | |
| SCHEMBL28636497 | 0.69 | ALDH1A1 (0.64) | TAAR1ACP1ALDH1A1TSHRCYP1A2 | |
| SCHEMBL13755994 | 0.65 | TAAR1 (0.59) | TAAR1EEDALDH1A1TSHRHSD17B10 | |
| SCHEMBL5915632 | 0.64 | TAAR1 (1.00) | TAAR1ALDH1A1TSHRHRH3 | |
| SCHEMBL15380931 | 0.62 | MEN1 (0.42) | TAAR1CHEK1 | |
| SCHEMBL17423360 | 0.62 | KDM1A (0.66) | ACP1 | |
| SCHEMBL28856265 | 0.60 | RAB9A (0.46) | CHEK1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL24735547 | 0.60 | TSHR (1.00) | TAAR1ALDH1A1TSHRCYP3A4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832091-B1 | C-4' MODIFIED ADENOSINE KINASE INHIBITORS | GENSIA SICOR INC (US) | 2004-01-14 | — | — | EP | disclosed |