Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | CA12 | O43570 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.63 |
| ▸ | CA4 | P22748 | 1/20 | 0.63 |
| ▸ | CA6 | P23280 | 1/20 | 0.63 |
| ▸ | CA7 | P43166 | 1/20 | 0.63 |
| ▸ | CA9 | Q16790 | 1/20 | 0.63 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.63 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.63 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | GSTA1 | P08263 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL8606279 | 0.92 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2HPGDKDM4ECA12 | |
| SCHEMBL1334176 | 0.92 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2HPGDKDM4ECA12 | |
| SCHEMBL11665831 | 0.90 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2HPGDKDM4ECA12 | |
| Salicylic Acid SCHEMBL3409946 | 0.88 | ALDH1A1 (0.82) | ALDH1A1SMN1; SMN2HPGDKDM4ECA12 | |
| Diethylamine SCHEMBL3323938 | 0.86 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2HPGDKDM4ECA12 | |
| Phthalic Acid SCHEMBL11577907 | 0.84 | AKR1C3 (0.76) | ALDH1A1SMN1; SMN2HPGDKDM4ECA12 | |
| SCHEMBL455832 | 0.83 | LIG1 (0.64) | ALDH1A1SMN1; SMN2HPGDKDM4ECA12 | |
| Phthalic Acid SCHEMBL5875168 | 0.83 | ALDH1A1 (0.78) | ALDH1A1SMN1; SMN2HPGDKDM4ECA12 | |
| Phthalic Acid SCHEMBL5875176 | 0.83 | ALDH1A1 (0.78) | ALDH1A1SMN1; SMN2HPGDKDM4ECA12 | |
| 2-Benzoylbenzoic Acid SCHEMBL11757908 | 0.82 | AKR1C3 (0.87) | ALDH1A1KDM4ECA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040242891-A1 | Production of keto acids | CAMPBELL JONATHAN (GB) | 2004-12-02 | — | — | US | disclosed |
| EP-1442009-A1 | PRODUCTION OF KETO ACIDS | Ciba SC Holding AG (CH) | 2004-08-04 | — | — | EP | disclosed |
| WO-2003037846-A1 | PRODUCTION OF KETO ACIDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-05-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242891-A1 | Production of keto acids | PKLR, KHK, ME1 | ALDH1A1 1103/4885SMN1; SMN2 3961/4885HPGD 1282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.