SCHEMBL6883947

SCHEMBL6883947

O=C(OC1(c2ccccc2)C=CC=CC1C(=O)O)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.41
F2 P00734 1/20 0.41
TSHR P16473 5/20 0.35
TDP1 Q9NUW8 3/20 0.34
ALDH1A1 P00352 3/20 0.34
HSD17B10 Q99714 1/20 0.34
HSD11B1 P28845 1/20 0.33
KMT2A Q03164 5/20 0.33
MAPT P10636 3/20 0.33
TP53 P04637 1/20 0.33
GAA P10253 1/20 0.32
MAPK1 P28482 1/20 0.32
HIF1A Q16665 1/20 0.32
POLB P06746 1/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A3 Q01959 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
NCOA3 Q9Y6Q9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11520353 0.84 GAA (0.36) TSHRTDP1ALDH1A1HSD17B10HSD11B1
SCHEMBL14689964 0.81 THRB (0.33) KMT2A
SCHEMBL21526684 0.80 ELANE (0.37)
SCHEMBL8420155 0.72 HSD11B1 (0.35) LMNAF2HSD11B1
SCHEMBL574722 0.70 HSD11B1 (0.36) LMNAHSD11B1
SCHEMBL9142790 0.69 HSD11B1 (0.35) LMNATDP1ALDH1A1HSD11B1KMT2A
Hydrochloric Acid SCHEMBL28568646 0.69 HSD11B1 (0.35) LMNATDP1ALDH1A1HSD11B1KMT2A
SCHEMBL27660328 0.69 HSD11B1 (0.35) LMNAHSD11B1
SCHEMBL31709146 0.68 LMNA (0.39) LMNAF2TSHRTDP1ALDH1A1
SCHEMBL1157442 0.67 HTT (0.35) LMNATSHRALDH1A1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6720287-B2 WHEN AN AROMATIC DICARBOXYLATE IS ENCAPSULATEDTOGETHER WITH THE DIAZONIUM SALT COMPOUND, GENERATION OF PHOTODECOMPOSITION STAIN IS REDUCED AND SHELF LIFE IS IMPROVED FUJI PHOTO FILM CO., LTD. (JP) 2004-04-13 US disclosed
US-20030045426-A1 Heat sensitive recording material and microcapsule solution FUJI PHOTO FILM CO., LTD. 2003-03-06 US disclosed