Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GGT1 | P19440 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21526684 | 0.86 | ELANE (0.37) | — | |
| SCHEMBL6883947 | 0.84 | LMNA (0.41) | GAAALDH1A1MAPK1HSD17B10TSHR | |
| SCHEMBL14689964 | 0.82 | THRB (0.33) | — | |
| SCHEMBL1157442 | 0.81 | HTT (0.35) | ALDH1A1KDM4ETSHRPOLBHTT | |
| SCHEMBL10448804 | 0.81 | GAA (0.35) | GAANPSR1ALDH1A1MAPK1HSD17B10 | |
| SCHEMBL11519877 | 0.80 | PDK2 (0.32) | ALDH1A1HSD17B10KDM4EESR1ITGB3 | |
| SCHEMBL17986195 | 0.79 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL17986192 | 0.79 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL11419786 | 0.73 | CYP3A4 (0.39) | ALDH1A1HSD17B10KDM4ETSHRHSD11B1 | |
| SCHEMBL574722 | 0.71 | HSD11B1 (0.36) | HSD11B1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4153691-A | 2-(CARBAMOYL PHENYL) 2-ACETOXYBENZOATE | BEECHAM GROUP LIMITED (GB) | 1979-05-08 | — | — | US | disclosed |