Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.36 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.36 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6883711 | 0.93 | NAMPT (0.35) | ALDH1A1LMNASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL6883870 | 0.87 | EZH2 (0.39) | PTGESWDR5 | |
| SCHEMBL6018618 | 0.82 | PTGES (0.40) | PTGESWDR5 | |
| SCHEMBL6878399 | 0.80 | PTGES (0.49) | PTGESLMNAPOLBMAPT | |
| SCHEMBL6883027 | 0.80 | PTGES (0.41) | PTGESALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL6884265 | 0.78 | WDR5 (0.40) | LMNAPOLBMAPTWDR5MAPK1 | |
| SCHEMBL6885308 | 0.78 | PIN1 (0.38) | ALDH1A1LMNAKCNJ6KCNJ5KCNJ3 | |
| SCHEMBL6017757 | 0.77 | KMT2A (0.39) | ALDH1A1LMNAKCNJ6KCNJ5KCNJ3 | |
| SCHEMBL6878304 | 0.75 | PTGES (0.42) | PTGESWDR5 | |
| SCHEMBL6884611 | 0.71 | CNR1 (0.39) | ALDH1A1LMNAPOLBWDR5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096128-A2 | HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-11-11 | — | — | WO | claimed |
| WO-2004096128-A2 | HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-11-11 | — | — | WO | disclosed |