Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPRB | P23467 | 1/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6564051 | 0.85 | MAOB (0.39) | FFAR1MAOBFFAR4 | |
| SCHEMBL6882532 | 0.84 | FFAR1 (0.36) | FFAR1FFAR4 | |
| SCHEMBL6888111 | 0.84 | FFAR1 (0.36) | FFAR1FFAR4 | |
| SCHEMBL6564184 | 0.74 | RORC (0.37) | RORCFFAR1MAOBNR1H2NR1H3 | |
| SCHEMBL6564174 | 0.74 | RORC (0.39) | RORCFFAR1MAOBNR1H2NR1H3 | |
| SCHEMBL6158466 | 0.72 | NOS1 (0.37) | FFAR1MAOBPPARG | |
| SCHEMBL3279973 | 0.71 | VDR (0.64) | MAOBNR4A1NR4A2NR4A3 | |
| SCHEMBL6883395 | 0.69 | VDR (0.41) | MAOBNR4A1NR4A2NR4A3 | |
| SCHEMBL6155753 | 0.69 | VDR (0.41) | MAOBNR4A1NR4A2NR4A3 | |
| SCHEMBL6885404 | 0.69 | CYSLTR2 (0.48) | FFAR1PPARGFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831106-B1 | Selective activity on cell proliferation and differentiation without displaying any hypercalcaemiant nature | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-12-14 | — | — | US | disclosed |