(Z)-1,2-Diphenylethene

(Z)-1,2-Diphenylethene

SCHEMBL6887768

C(=C/c1ccccc1)\c1ccccc1.CCC#N.CCC#N

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RELA Q04206 2/20 0.50
CHAT P28329 2/20 0.46
MAOB P27338 2/20 0.46
HTR2A P28223 3/20 0.45
TRPA1 O75762 1/20 0.45
NFE2L2 Q16236 1/20 0.44
CYP19A1 P11511 1/20 0.44
MAOA P21397 1/20 0.44
GRM5 P41594 1/20 0.44
IDO1 P14902 1/20 0.43
PAM P19021 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Z)-1,2-Diphenylethene SCHEMBL6887771 1.00 RELA (0.50) RELACHATMAOBHTR2ATRPA1
Styrene SCHEMBL27560899 0.82 ALDH1A1 (0.61) RELAHTR2A
(Z)-1,2-Diphenylethene SCHEMBL27660887 0.79 MAOB (0.55) RELACHATMAOBTRPA1NFE2L2
(Z)-1,2-Diphenylethene SCHEMBL27373856 0.79 MAOB (0.69) RELACHATMAOBTRPA1NFE2L2
(Z)-1,2-Diphenylethene SCHEMBL28743228 0.79 MAOB (0.69) RELACHATMAOBTRPA1NFE2L2
(Z)-1,2-Diphenylethene SCHEMBL28212372 0.77 MAOB (0.52) RELACHATMAOBTRPA1NFE2L2
(Z)-1,2-Diphenylethene SCHEMBL28118204 0.77 MAOB (0.52) RELACHATMAOBTRPA1NFE2L2
(Z)-1,2-Diphenylethene SCHEMBL1679623 0.77 NFE2L2 (0.56) RELACHATMAOBTRPA1NFE2L2
Biphenyl SCHEMBL27433633 0.77 ALDH1A1 (0.50)
SCHEMBL1002069 0.76 MAOB (0.49) MAOBHTR2AMAOAIDO1PAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1490330-A2 POLYMER BOUND DONOR-ACCEPTOR-DONOR COMPOUNDS AND THEIR USE IN A 3-DIMENSIONAL OPTICAL MEMORY Mempile Inc. (US) 2004-12-29 EP disclosed
WO-2003070689-A2 POLYMER BOUND DONOR-ACCEPTOR-DONOR COMPOUNDS AND THEIR USE IN A 3-DIMENSIONAL OPTICAL MEMORY MEMPILE INC. (US) 2003-08-28 WO disclosed