SCHEMBL688880

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29977311	0.86	ALDH1A1 (0.59)	IDO1EP300KAT8HDAC3KAT2B
	SCHEMBL689722	0.86	ALDH1A1 (0.59)	IDO1EP300KAT8HDAC3KAT2B
	SCHEMBL5179481	0.85	IMPDH2 (0.37)	IDO1ALDH1A1TSHRHSD17B10TDP1
	SCHEMBL630084	0.77	IMPDH2 (0.52)	IDO1EP300KAT8HDAC3KAT2B
	SCHEMBL8590439	0.77	IDO1 (0.46)	IDO1EP300KAT8HDAC3KAT2B
	SCHEMBL30175215	0.77	IMPDH2 (0.52)	IDO1EP300KAT8HDAC3KAT2B
	SCHEMBL29404342	0.77	ALDH1A1 (0.73)	IDO1EP300KAT8HDAC3KAT2B
	SCHEMBL201893	0.77	ALDH1A1 (0.73)	IDO1EP300KAT8HDAC3KAT2B
	SCHEMBL690482	0.77	ALDH1A1 (0.36)	ALDH1A1CYP3A4HPGDTSHRHSD17B10
	SCHEMBL6894903	0.75	FABP7 (0.39)	ALDH1A1CYP3A4HPGDTSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.