Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45391 | 0.76 | HTR7 (0.36) | KMT2AMEN1NPSR1CA1CA2 | |
| SCHEMBL3165966 | 0.73 | TTR (0.35) | TSHRSMN1; SMN2CA1CA2POLB | |
| SCHEMBL2319486 | 0.73 | NCOR2 (0.42) | TSHRKMT2AMAPTMEN1HTT | |
| SCHEMBL29945031 | 0.73 | NCOR2 (0.42) | TSHRKMT2AMAPTMEN1HTT | |
| SCHEMBL1683233 | 0.72 | ALDH1A1 (0.49) | KMT2AMAPTMEN1SMN1; SMN2ALDH1A1 | |
| Dimethyl Phthalate SCHEMBL27641225 | 0.71 | CA1 (0.63) | TSHRKMT2AMAPTCA1CA2 | |
| SCHEMBL8697389 | 0.70 | AKR1B1 (0.41) | TSHRMAPT | |
| SCHEMBL1934600 | 0.70 | ALDH1A1 (0.40) | TSHRKMT2AMAPTMEN1HTT | |
| SCHEMBL114462 | 0.70 | CA1 (0.35) | KMT2AMAPTHTTSMN1; SMN2NPSR1 | |
| SCHEMBL5818114 | 0.70 | CA1 (0.33) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696605-B2 | CATALYTICALLY REACTING POLYMER SUPPORTED ISOCYANIDE WITH ALDEHYDE; OPTIONALLY OXIDIZING; CLEAVING NITROGEN RESIN BOND | THE PROCTER & GAMBLE COMPANY | 2004-02-24 | — | — | US | claimed |
| US-20030176739-A1 | Process for preparing alpha-hydroxyamides and alpha-ketoamides on a solid phase support | THE PROCTER & GAMBLE COMPANY | 2003-09-18 | — | — | US | claimed |
| US-6696605-B2 | CATALYTICALLY REACTING POLYMER SUPPORTED ISOCYANIDE WITH ALDEHYDE; OPTIONALLY OXIDIZING; CLEAVING NITROGEN RESIN BOND | THE PROCTER & GAMBLE COMPANY | 2004-02-24 | — | — | US | disclosed |
| US-20030176739-A1 | Process for preparing alpha-hydroxyamides and alpha-ketoamides on a solid phase support | THE PROCTER & GAMBLE COMPANY | 2003-09-18 | — | — | US | disclosed |
| US-5684127-A | SELECTIVELY PROTECTING AMINO GROUPS AND PHENOLIC HYDROXY GROUPS OF A PENTAPEPTIDE, OXIDIZING THE HYDROXYMETHYL MOIETY OF PROTECTED PENTAPEPTIDE TO CARBOXY, DEPROTECTING AMINO GROUP AND SUBMITTING COMPOUND TO DEGRADATION | GRUPPO LEPETIT SPA (IT) | 1997-11-04 | — | — | US | disclosed |
| US-5644025-A | AGLYCON DALBAHEPTIDE ANTIBIOTICS FOR CYCLIC TETRAPEPTIDES FOR BACTERICIDES | GRUPPO LEPETIT SPA (IT) | 1997-07-01 | — | — | US | disclosed |
| EP-0363211-B1 | 1Alpha or 24R,25-Dihydroxy vitamin D3 derivatives, process for their production and assay method using the same | ASAHI CHEMICAL IND (JP) | 1994-07-06 | — | — | EP | disclosed |
| US-5214170-A | Radioimmunoassay | TOYO JOZO KABUSHIKI KAISHA (JP) | 1993-05-25 | — | — | US | disclosed |
| US-5202266-A | 25-hydroxy vitamin D3 derivatives, process for their production, and assay method using the same | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0312360-B1 | 25-HYDROXY VITAMIN D3 DERIVATIVES | TOYO JOZO KABUSHIKI KAISHA (JP) | 1992-06-17 | — | — | EP | disclosed |
| US-5117018-A | 1α (or 24R), 25-dihydroxy vitamin D3 derivatives | TOYO JOZO KABUSHIKI KAISHA (JP) | 1992-05-26 | — | — | US | disclosed |
| US-5075465-A | 25-HYDROXY VITAMIN D3 DERIVATIVES, PROCESS FOR THEIR PRODUCTION, AND ASSAY METHOD USING THE SAME | TOYO JOZO KABUSHIKI KAISHA (JP) | 1991-12-24 | — | — | US | disclosed |
| EP-0363211-A1 | 1Alpha or 24R,25-Dihydroxy vitamin D3 derivatives, process for their production and assay method using the same | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1990-04-11 | — | — | EP | disclosed |
| EP-0312360-A2 | 25-Hydroxy vitamin D3 derivatives | TOYO JOZO KABUSHIKI KAISHA (JP) | 1989-04-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176739-A1 | Process for preparing alpha-hydroxyamides and alpha-ketoamides on a solid phase support | KDM8, HACL2, HAAO | TSHR 4202/4885KMT2A 19/4885MAPT 3156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.