SCHEMBL6889478

SCHEMBL6889478

COc1cc2c3c(c4c(c2cc1N1CCCCC1)-c1ccccc1C4(c1ccccc1)c1ccccc1)OC(c1ccccc1)(c1ccc(N(C)C)cc1)C=C3

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6889518 0.93 BCHE (0.32)
SCHEMBL6888011 0.86 STK10 (0.34)
SCHEMBL6889466 0.85 LPAR5 (0.30)
SCHEMBL6887823 0.81 STK10 (0.33)
SCHEMBL19901121 0.80 MAPT (0.30)
SCHEMBL6886646 0.79 TDP1 (0.32)
SCHEMBL6888729 0.79 BCHE (0.32)
SCHEMBL13988310 0.78 SLC6A3 (0.31)
SCHEMBL2023151 0.78 DRD2 (0.31)
SCHEMBL23800760 0.76 HTR7 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6686468-B2 FOR USE IN SYNTHETIC RESINS TO OBTAIN VIOLET TO BLUE TINTS; USED IN PHOTOTROPIC GLASSES OPTISCHE WERKE G. RODENSTOCK (DE) 2004-02-03 US claimed
EP-1235823-B1 H-ANNELLATED BENZO [F]CHROMENES RODENSTOCK OPTIK G (DE) 2003-07-16 EP claimed
US-20030040623-A1 For use in synthetic resins to obtain violet to blue tints; used in phototropic glasses RODENSTOCK GMBH (DE) 2003-02-27 US claimed
US-6686468-B2 FOR USE IN SYNTHETIC RESINS TO OBTAIN VIOLET TO BLUE TINTS; USED IN PHOTOTROPIC GLASSES OPTISCHE WERKE G. RODENSTOCK (DE) 2004-02-03 US disclosed
EP-1235823-B1 H-ANNELLATED BENZO [F]CHROMENES RODENSTOCK OPTIK G (DE) 2003-07-16 EP disclosed
US-20030040623-A1 For use in synthetic resins to obtain violet to blue tints; used in phototropic glasses RODENSTOCK GMBH (DE) 2003-02-27 US disclosed
EP-1235823-A1 H-ANNELLATED BENZO F]CHROMENES Optische Werke G. Rodenstock (DE) 2002-09-04 EP disclosed
WO-2002022594-A1 H-ANNELLATED BENZO[F]CHROMENES OPTISCHE WERKE G. RODENSTOCK (DE) 2002-03-21 WO disclosed