Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 6/20 | 0.51 |
| ▸ | FPR1 | P21462 | 4/20 | 0.51 |
| ▸ | HRAS | P01112 | 3/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6885351 | 0.77 | HRAS (0.43) | FPR2FPR1HRASITGB3ITGA2B | |
| SCHEMBL6890914 | 0.77 | LTA4H (0.41) | HRASMMP9MMP8PPARGLTA4H | |
| Trifluoroacetic Acid SCHEMBL8645040 | 0.74 | MMP9 (0.48) | MMP9MMP8MMEACECPA1 | |
| SCHEMBL8615470 | 0.74 | MMP9 (0.53) | HRASMMP9MMP8MMEACE | |
| SCHEMBL3499760 | 0.73 | LTA4H (0.65) | MMP9MMP8MMEACECPA1 | |
| SCHEMBL3499757 | 0.73 | LTA4H (0.65) | MMP9MMP8MMEACECPA1 | |
| SCHEMBL8760872 | 0.73 | PPARG (0.67) | MMP9MMP8MMEACECPA1 | |
| SCHEMBL2035189 | 0.73 | PPARG (0.67) | MMP9MMP8MMEACECPA1 | |
| SCHEMBL2030203 | 0.73 | PPARG (0.67) | MMP9MMP8MMEACECPA1 | |
| Hydrochloric Acid SCHEMBL29693844 | 0.72 | LTA4H (0.64) | MMP9MMP8MMEACECPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6737410-B1 | SMOOTH MUSCLE ANTIPROLIFERATION AGENTS; SUCH AS 1-((2-(4-BENZYLOXY-PHENYL)-1-PHENETHYLCARBAMOYL-ETHYL)-METHYL-CARBAMOYL)-2 -(1H-IMIDAZOL-4-YL)-ETHYL)-CARBAMIC ACID BENZYL ESTER | WARNER-LAMBERT COMPANY | 2004-05-18 | — | — | US | disclosed |
| US-6265382-B1 | E.G., (S--(R*, R*))-(1-((2-(4-BENZYLOXY-PHENYL)-1-PHENETHYLCARBAMOYL-ETHYL)-M ETHYL-CARBAM OYL)-2-(1H-IMIDAZOL-4-YL)-ETHYL)-CARBAMIC ACID BENZYL ESTER | WARNER-LAMBERT COMPANY | 2001-07-24 | — | — | US | disclosed |
| WO-1998046625-A1 | DIPEPTIDE INHIBITORS OF PROTEIN FARNESYLTRANSFERASE | WARNER-LAMBERT COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |