Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRAS | P01112 | 3/20 | 0.43 |
| ▸ | FPR1 | P21462 | 2/20 | 0.42 |
| ▸ | FPR2 | P25090 | 2/20 | 0.42 |
| ▸ | YAP1 | P46937 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.39 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.39 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.39 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6890928 | 0.82 | PSMB1 (0.49) | MAOBBCL2MMP13PSMB1PSMB9 | |
| SCHEMBL6890932 | 0.82 | PSMB1 (0.49) | MAOBBCL2MMP13PSMB1PSMB9 | |
| SCHEMBL6890591 | 0.81 | EPOR (0.52) | MAOBITGB3ITGA2BBCL2SMN1; SMN2 | |
| SCHEMBL6892246 | 0.81 | MAOB (0.44) | HRASYAP1MAOBITGB3ITGA2B | |
| SCHEMBL16634946 | 0.79 | ITGB3 (0.55) | YAP1MAOBITGB3ITGA2BLTA4H | |
| SCHEMBL6474783 | 0.79 | ITGB3 (0.55) | YAP1MAOBITGB3ITGA2BLTA4H | |
| SCHEMBL29397771 | 0.79 | ITGB3 (0.55) | YAP1MAOBITGB3ITGA2BLTA4H | |
| SCHEMBL18918265 | 0.78 | LTA4H (0.52) | YAP1MAOBITGB3ITGA2BBCL2 | |
| Trifluoroacetic Acid SCHEMBL6890911 | 0.77 | FPR2 (0.51) | HRASFPR1FPR2ITGB3ITGA2B | |
| SCHEMBL6885353 | 0.76 | YAP1 (0.46) | YAP1MAOBITGB3ITGA2BBCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6737410-B1 | SMOOTH MUSCLE ANTIPROLIFERATION AGENTS; SUCH AS 1-((2-(4-BENZYLOXY-PHENYL)-1-PHENETHYLCARBAMOYL-ETHYL)-METHYL-CARBAMOYL)-2 -(1H-IMIDAZOL-4-YL)-ETHYL)-CARBAMIC ACID BENZYL ESTER | WARNER-LAMBERT COMPANY | 2004-05-18 | — | — | US | disclosed |
| US-6265382-B1 | E.G., (S--(R*, R*))-(1-((2-(4-BENZYLOXY-PHENYL)-1-PHENETHYLCARBAMOYL-ETHYL)-M ETHYL-CARBAM OYL)-2-(1H-IMIDAZOL-4-YL)-ETHYL)-CARBAMIC ACID BENZYL ESTER | WARNER-LAMBERT COMPANY | 2001-07-24 | — | — | US | disclosed |