Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 10/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CHUK | O15111 | 3/20 | 0.32 |
| ▸ | EPHA3 | P29320 | 3/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29061326 | 0.79 | GPR35 (0.44) | ALDH1A1HPGDGAAL3MBTL1 | |
| SCHEMBL28068800 | 0.73 | POLB (0.39) | ALDH1A1HSD17B10ALOX15POLBL3MBTL1 | |
| SCHEMBL2689405 | 0.69 | IKBKB (0.43) | IKBKBALDH1A1HSD17B10HPGDALOX15 | |
| SCHEMBL12319458 | 0.69 | ALDH1A1 (0.49) | IKBKBALDH1A1HSD17B10HPGDALOX15 | |
| SCHEMBL28273750 | 0.68 | ALDH1A1 (0.41) | ALDH1A1HSD17B10HPGDALOX15MEN1 | |
| SCHEMBL6891332 | 0.68 | POLB (0.34) | ALDH1A1HSD17B10POLBMEN1KMT2A | |
| SCHEMBL28613210 | 0.68 | LDHA (0.43) | ALDH1A1HSD17B10HPGDPOLBMEN1 | |
| SCHEMBL18701590 | 0.67 | GPR35 (0.39) | L3MBTL1 | |
| SCHEMBL29061340 | 0.67 | GPR35 (0.53) | ALDH1A1HSD17B10HPGDALOX15L3MBTL1 | |
| SCHEMBL3077087 | 0.66 | PKM (0.43) | IKBKBALDH1A1HSD17B10GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |