Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3005720 | 0.79 | CYP1A2 (0.44) | MEN1KMT2AHSD17B3 | |
| SCHEMBL28068800 | 0.73 | POLB (0.39) | POLBMEN1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL6890917 | 0.68 | IKBKB (0.40) | POLBMEN1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL28273750 | 0.68 | ALDH1A1 (0.41) | MEN1ALDH1A1KMT2AHSD17B10SIRT1 | |
| SCHEMBL28613210 | 0.68 | LDHA (0.43) | POLBMEN1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL2996746 | 0.67 | CYP1A2 (0.41) | MEN1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL30758065 | 0.66 | ALOX5 (0.40) | POLBMEN1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL2964481 | 0.65 | PARP1 (0.45) | MEN1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL3179817 | 0.65 | GRIA1 (0.44) | POLBMEN1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL11240281 | 0.64 | POLB (0.50) | POLBALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |