Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 1/20 | 0.49 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.49 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | EPOR | P19235 | 3/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6890932 | 1.00 | PSMB1 (0.49) | PSMB1PSMB8PSMB9PSMB5EPHX2 | |
| SCHEMBL6890591 | 0.90 | EPOR (0.52) | MAOBEPORBCL2REN | |
| SCHEMBL7948670 | 0.89 | EPHX2 (0.52) | EPHX2MAOBFFAR1FFAR4EPOR | |
| SCHEMBL7948674 | 0.89 | EPHX2 (0.52) | EPHX2MAOBFFAR1FFAR4EPOR | |
| SCHEMBL6892246 | 0.87 | MAOB (0.44) | PSMB1PSMB8PSMB9PSMB5MAOB | |
| SCHEMBL6474783 | 0.85 | ITGB3 (0.55) | MAOBFFAR1FFAR4 | |
| SCHEMBL29397771 | 0.85 | ITGB3 (0.55) | MAOBFFAR1FFAR4 | |
| SCHEMBL16634946 | 0.85 | ITGB3 (0.55) | MAOBFFAR1FFAR4 | |
| SCHEMBL18918265 | 0.83 | LTA4H (0.52) | MAOBFFAR1FFAR4BCL2LTB4R | |
| SCHEMBL6885351 | 0.82 | HRAS (0.43) | PSMB1PSMB8PSMB9PSMB5MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6737410-B1 | SMOOTH MUSCLE ANTIPROLIFERATION AGENTS; SUCH AS 1-((2-(4-BENZYLOXY-PHENYL)-1-PHENETHYLCARBAMOYL-ETHYL)-METHYL-CARBAMOYL)-2 -(1H-IMIDAZOL-4-YL)-ETHYL)-CARBAMIC ACID BENZYL ESTER | WARNER-LAMBERT COMPANY | 2004-05-18 | — | — | US | disclosed |