Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | EPOR | P19235 | 3/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.47 |
| ▸ | LAP3 | P28838 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7948674 | 1.00 | EPHX2 (0.52) | EPHX2ITGB3ITGA2BMAOBFFAR1 | |
| SCHEMBL6890932 | 0.89 | PSMB1 (0.49) | EPHX2MAOBFFAR1FFAR4EPOR | |
| SCHEMBL6890928 | 0.89 | PSMB1 (0.49) | EPHX2MAOBFFAR1FFAR4EPOR | |
| SCHEMBL10945054 | 0.87 | SIGMAR1 (0.50) | ITGB3ITGA2BSIGMAR1 | |
| SCHEMBL10790060 | 0.84 | ITGB3 (0.66) | ITGB3ITGA2BMAOBFFAR1FFAR4 | |
| SCHEMBL10946295 | 0.83 | ITGB3 (0.53) | ITGB3ITGA2BMAOBLTA4HLAP3 | |
| SCHEMBL10944294 | 0.82 | LTA4H (0.52) | ITGB3ITGA2BMAOBLTA4HEPOR | |
| SCHEMBL10942526 | 0.81 | NPC1 (0.49) | ITGB3ITGA2BMAOBLTA4HLAP3 | |
| SCHEMBL6890591 | 0.79 | EPOR (0.52) | ITGB3ITGA2BMAOBEPOR | |
| SCHEMBL6885238 | 0.79 | HRAS (0.46) | EPHX2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265382-B1 | E.G., (S--(R*, R*))-(1-((2-(4-BENZYLOXY-PHENYL)-1-PHENETHYLCARBAMOYL-ETHYL)-M ETHYL-CARBAM OYL)-2-(1H-IMIDAZOL-4-YL)-ETHYL)-CARBAMIC ACID BENZYL ESTER | WARNER-LAMBERT COMPANY | 2001-07-24 | — | — | US | disclosed |