Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | THRB | P10828 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 2/20 | 0.37 |
| ▸ | YWHAG | P61981 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688778 | 0.85 | CSNK2A1 (0.37) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL688883 | 0.84 | KEAP1 (0.38) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL689301 | 0.84 | PTPRC (0.34) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL17774836 | 0.80 | HTT (0.44) | MAPTMEN1KMT2ATHRBKDM4E | |
| SCHEMBL15490163 | 0.74 | MAPT (0.46) | MAPTMEN1KMT2ATHRBKDM4E | |
| SCHEMBL29793691 | 0.74 | MAPT (0.46) | MAPTMEN1KMT2ATHRBKDM4E | |
| SCHEMBL17774772 | 0.74 | HCAR3 (0.40) | MAPTMEN1KMT2ATHRBKDM4E | |
| SCHEMBL17774833 | 0.73 | MEN1 (0.37) | MAPTMEN1KMT2ATHRBKDM4E | |
| Hydrochloric Acid SCHEMBL15486878 | 0.73 | MAPT (0.44) | MAPTMEN1KMT2ATHRBKDM4E | |
| SCHEMBL2002664 | 0.71 | PTGDR2 (0.44) | MAPTKDM4EALOX15ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953148-B1 | HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2012-02-29 | — | — | EP | disclosed |
| US-7915267-B2 | Heterocyclic amide compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-03-29 | — | — | US | disclosed |