Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL689128 | 0.85 | MAPT (0.37) | MEN1KMT2APKMALDH1A1POLB | |
| SCHEMBL689301 | 0.84 | PTPRC (0.34) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL688883 | 0.84 | KEAP1 (0.38) | MEN1KMT2AALDH1A1PARP1GLA | |
| SCHEMBL688072 | 0.80 | TP53 (0.56) | MEN1KMT2APKMALDH1A1POLB | |
| SCHEMBL28587927 | 0.74 | CSNK2A1 (0.35) | CSNK2A1MEN1KMT2APOLBPARP1 | |
| SCHEMBL14048151 | 0.74 | ALDH1A1 (0.42) | CSNK2A1MEN1KMT2AALDH1A1PARP1 | |
| SCHEMBL2002664 | 0.71 | PTGDR2 (0.44) | ALDH1A1POLBGLATSHRMAPT | |
| SCHEMBL688887 | 0.71 | LMNA (0.41) | MEN1KMT2AALDH1A1POLBGLA | |
| SCHEMBL11591359 | 0.69 | MAPT (0.35) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL689046 | 0.67 | RORC (0.40) | ALDH1A1GLATSHRMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953148-B1 | HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2012-02-29 | — | — | EP | disclosed |
| US-7915267-B2 | Heterocyclic amide compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-03-29 | — | — | US | disclosed |