Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | KLK7 | P49862 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL924496 | 0.95 | KMT2A (0.63) | KMT2AMEN1ALDH1A1GAAKLK7 | |
| SCHEMBL68930 | 0.89 | CYP4Z1 (0.57) | ALDH1A1GAAL3MBTL1MAPTHSD17B10 | |
| Propionaldehyde SCHEMBL1136027 | 0.87 | KMT2A (0.56) | KMT2AMEN1ALDH1A1GAAKLK7 | |
| SCHEMBL19068066 | 0.84 | HTT (0.62) | KMT2AALDH1A1GAAKLK7L3MBTL1 | |
| SCHEMBL12126600 | 0.84 | CYP4Z1 (0.53) | KMT2AMEN1ALDH1A1L3MBTL1HTT | |
| SCHEMBL432816 | 0.84 | CYP4F2 (0.64) | KMT2AALDH1A1L3MBTL1TDP1GLA | |
| SCHEMBL68851 | 0.84 | CYP4Z1 (0.62) | KMT2AMEN1ALDH1A1GAAL3MBTL1 | |
| SCHEMBL3227634 | 0.83 | GAA (0.58) | KMT2AMEN1ALDH1A1GAAL3MBTL1 | |
| SCHEMBL11363373 | 0.83 | SENP1 (0.53) | KMT2AMEN1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL11837941 | 0.83 | ALDH1A1 (0.50) | KMT2AMEN1ALDH1A1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438754-B1 | Optically active compound, intermediate therefor, process for producing the intermediate, and liquid-crystal composition | DAINIPPON INK & CHEMICALS (JP) | 1994-08-17 | — | — | EP | disclosed |
| US-5064564-A | Ferroelectric liquid crystal display | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1991-11-12 | — | — | US | disclosed |
| EP-0438754-A1 | Optically active compound, intermediate therefor, process for producing the intermediate, and liquid-crystal composition | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1991-07-31 | — | — | EP | disclosed |
| US-4431660-A | UROGENITAL DISORDERS; ENZYME INHIBITORS; KIDNEY AND BLADDER STONES | MERCK & CO., INC. (US) | 1984-02-14 | — | — | US | disclosed |
| US-4256758-A | 4-Substituted-3-hydroxy-3-pyrroline-2,5-dione inhibitors of glycolic acid oxidase | MERCK & CO., INC. (US) | 1981-03-17 | — | — | US | disclosed |