Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9125159 | 0.62 | CHRNB2 (0.35) | BACE1 | |
| SCHEMBL14144112 | 0.60 | OPRD1 (0.41) | — | |
| SCHEMBL12823209 | 0.60 | TSHR (0.41) | BACE1KCNH2 | |
| SCHEMBL932151 | 0.59 | CHRNA1 (0.35) | BACE1 | |
| SCHEMBL23715176 | 0.59 | SIGMAR1 (0.33) | BACE1KCNH2 | |
| SCHEMBL22306764 | 0.58 | OPRD1 (0.39) | — | |
| SCHEMBL2735490 | 0.57 | — | — | |
| SCHEMBL764969 | 0.57 | — | — | |
| SCHEMBL8222072 | 0.57 | — | — | |
| SCHEMBL12886827 | 0.57 | ACHE (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011002408-A1 | NOVEL COMPOUNDS FOR TREATMENT OF NEURODEGENERATION ASSOCIATED WITH DISEASES, SUCH AS ALZHEIMER'S DISEASE OR DEMENTIA | ASTRAZENECA AB (SE) | 2011-01-06 | — | — | WO | disclosed |