Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | PNPLA2 | Q96AD5 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL534366 | 0.78 | ROCK2 (0.43) | MAPTROCK2NPSR1ALDH1A1KDM4E | |
| SCHEMBL13107778 | 0.77 | ALDH1A1 (0.57) | MAPTHTTNPSR1ALDH1A1HDAC6 | |
| SCHEMBL27849607 | 0.77 | MAPT (0.40) | MAPTHTTNPSR1ALDH1A1PNPLA2 | |
| SCHEMBL5046029 | 0.76 | RAB9A (0.46) | MAPTHTTROCK2ALDH1A1HPGD | |
| SCHEMBL29447175 | 0.76 | APEX1 (0.57) | MAPTROCK2ALDH1A1APEX1 | |
| SCHEMBL29447176 | 0.76 | APEX1 (0.57) | MAPTROCK2ALDH1A1APEX1 | |
| SCHEMBL138240 | 0.76 | APEX1 (0.57) | MAPTROCK2ALDH1A1APEX1 | |
| SCHEMBL13365642 | 0.74 | NPSR1 (0.43) | MAPTNPSR1ALDH1A1HDAC6KDM4E | |
| SCHEMBL9408595 | 0.74 | ROCK2 (0.59) | MAPTROCK2ALDH1A1HDAC6KDM4E | |
| SCHEMBL28567911 | 0.73 | GPBAR1 (0.45) | MAPTROCK2ALDH1A1KDM4EAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2295483-B1 | Low temperature curable epoxy compositions containing urea curatives | AIR PROD & CHEM (US) | 2014-10-29 | — | — | EP | disclosed |
| EP-2295486-B1 | Low temperature curable epoxy compositions containing phenolic-blocked urea curatives | AIR PROD & CHEM (US) | 2012-02-29 | — | — | EP | disclosed |
| US-7910667-B1 | Low temperature curable epoxy compositions containing phenolic-blocked urea curatives | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2011-03-22 | — | — | US | disclosed |
| US-20110065837-A1 | LOW TEMPERATURE CURABLE EPOXY COMPOSITIONS CONTAINING PHENOLIC-BLOCKED UREA CURATIVES | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2011-03-17 | — | — | US | disclosed |
| EP-2295486-A1 | Low temperature curable epoxy compositions containing phenolic-blocked urea curatives | Air Products and Chemicals, Inc. (US) | 2011-03-16 | — | — | EP | disclosed |
| EP-2295483-A1 | Low temperature curable epoxy compositions containing urea curatives | Air Products and Chemicals, Inc. (US) | 2011-03-16 | — | — | EP | disclosed |