SCHEMBL68963

SCHEMBL68963

O=C(Oc1noc2ccccc12)c1cccc(C(=O)Oc2noc3ccccc23)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 6/20 0.50
SMN1; SMN2 Q16637 5/20 0.45
TP53 P04637 4/20 0.45
FAAH O00519 2/20 0.41
MGLL Q99685 1/20 0.41
KMT2A Q03164 4/20 0.41
MEN1 O00255 3/20 0.41
ESR1 P03372 3/20 0.41
ESR2 Q92731 3/20 0.41
MAPT P10636 3/20 0.41
GAA P10253 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
JAK2 O60674 1/20 0.41
USP2 O75604 1/20 0.41
ALOX15 P16050 1/20 0.41
HSD17B10 Q99714 1/20 0.41
ALDH1A1 P00352 3/20 0.41
POLB P06746 1/20 0.40
LMNA P02545 1/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14427253 0.91 MAPT (0.47) HIF1ASMN1; SMN2TP53FAAHMGLL
SCHEMBL70238 0.89 SMN1; SMN2 (0.45) HIF1ASMN1; SMN2TP53FAAHMGLL
SCHEMBL14775860 0.79 HIF1A (0.47) HIF1ASMN1; SMN2TP53FAAHMGLL
SCHEMBL25255597 0.78 FAAH (0.49) HIF1ASMN1; SMN2TP53FAAHMGLL
SCHEMBL10520166 0.78 FAAH (0.45) HIF1ASMN1; SMN2TP53FAAHMGLL
SCHEMBL28103593 0.74 ALDH1A1 (0.46) HIF1ASMN1; SMN2TP53FAAHMGLL
SCHEMBL5649712 0.70 KMT2A (0.50) HIF1ASMN1; SMN2TP53FAAHMGLL
SCHEMBL10659456 0.69 FAAH (0.54) HIF1ASMN1; SMN2TP53FAAHMGLL
SCHEMBL6988473 0.68 FAAH (0.43) HIF1ASMN1; SMN2TP53FAAHMGLL
SCHEMBL6972027 0.68 FAAH (0.51) HIF1ASMN1; SMN2TP53FAAHMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed