SCHEMBL70238

SCHEMBL70238

O=C(Oc1noc2ccccc12)c1ccc(C(=O)Oc2noc3ccccc23)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 6/20 0.45
TP53 P04637 4/20 0.45
MAPT P10636 4/20 0.45
FAAH O00519 2/20 0.44
MGLL Q99685 1/20 0.44
HIF1A Q16665 8/20 0.43
KMT2A Q03164 3/20 0.41
ALDH1A1 P00352 3/20 0.41
MEN1 O00255 2/20 0.41
GAA P10253 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
LMNA P02545 1/20 0.41
HTT P42858 1/20 0.41
HSD17B10 Q99714 2/20 0.41
JAK2 O60674 1/20 0.41
USP2 O75604 1/20 0.41
ESR1 P03372 1/20 0.41
ALOX15 P16050 1/20 0.41
ESR2 Q92731 1/20 0.41
SSTR4 P31391 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14427253 0.95 MAPT (0.47) SMN1; SMN2TP53MAPTFAAHMGLL
SCHEMBL68963 0.89 HIF1A (0.50) SMN1; SMN2TP53MAPTFAAHMGLL
SCHEMBL14775860 0.83 HIF1A (0.47) SMN1; SMN2TP53MAPTFAAHMGLL
SCHEMBL25255597 0.81 FAAH (0.49) SMN1; SMN2TP53MAPTFAAHMGLL
SCHEMBL10520166 0.81 FAAH (0.45) SMN1; SMN2TP53MAPTFAAHMGLL
SCHEMBL28103593 0.78 ALDH1A1 (0.46) SMN1; SMN2TP53MAPTFAAHMGLL
SCHEMBL5649712 0.73 KMT2A (0.50) SMN1; SMN2TP53MAPTFAAHMGLL
SCHEMBL10659456 0.72 FAAH (0.54) SMN1; SMN2TP53FAAHMGLLHIF1A
SCHEMBL6988473 0.71 FAAH (0.43) SMN1; SMN2TP53MAPTFAAHMGLL
SCHEMBL6972027 0.71 FAAH (0.51) SMN1; SMN2TP53FAAHMGLLHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
US-5015698-A Polyphenylene ether-polyester copolymers, precursors therefor, compositions containing said copolymers, and methods for their preparation GENERAL ELECTRIC COMPANY (US) 1991-05-14 US disclosed
EP-0248263-A2 Polyphenylene ether-polyester copolymers precursors therefor, compositions containing said copolymers, and methods for their preparation GENERAL ELECTRIC COMPANY (US) 1987-12-09 EP disclosed
WO-1987007279-A1 POLYPHENYLENE ETHER-POLYESTER COPOLYMERS, PRECURSORS THEREFOR, COMPOSITIONS CONTAINING SAID COPOLYMERS, AND METHODS FOR THEIR PREPARATION GENERAL ELECTRIC COMPANY (US) 1987-12-03 WO disclosed