Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 3/20 | 0.33 |
| ▸ | CES1 | P23141 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4952380 | 0.85 | LMNA (0.35) | LMNAF2MAPTNPC1MAPK1 | |
| SCHEMBL4199640 | 0.84 | AKR1C1 (0.40) | LMNAKMT2ATSHRAKR1C1ALDH1A1 | |
| SCHEMBL5496475 | 0.80 | LMNA (0.43) | LMNAF2MAPTNPC1MAPK1 | |
| SCHEMBL1551316 | 0.79 | LMNA (0.40) | LMNAF2MAPTNPC1MAPK1 | |
| SCHEMBL6204352 | 0.76 | AKR1C1 (0.39) | LMNAF2MAPTNPC1MAPK1 | |
| SCHEMBL9800616 | 0.76 | LMNA (0.38) | LMNAF2MAPTNPC1MAPK1 | |
| SCHEMBL9859980 | 0.73 | LMNA (0.39) | LMNAF2MAPTNPC1MAPK1 | |
| SCHEMBL230776 | 0.72 | AKR1C1 (0.45) | LMNAKMT2ATSHRAKR1C1ALDH1A1 | |
| SCHEMBL22872421 | 0.70 | MAPT (0.40) | LMNAF2MAPTNPC1MAPK1 | |
| SCHEMBL11490512 | 0.70 | NPSR1 (0.37) | LMNAMAPTNPC1MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180132516-A1 | POSITIVE ALLOSTERIC MODULATORS OF SWEET TASTE | SENSORYGEN INC (US) | 2018-05-17 | — | — | US | disclosed |
| US-6780883-B2 | ANTICHOLESTEROL AGENTS; CARDIOVASCULAR DISORDERS; ANTILIPEMIC AGENTS; RESTENOSIS; DIETETICS | WARNER-LAMBERT COMPANY | 2004-08-24 | — | — | US | disclosed |