Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | ADH4 | P08319 | 1/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6895292 | 1.00 | SPHK1 (0.52) | SPHK1OPRM1TP53S1PR2S1PR1 | |
| SCHEMBL11299774 | 0.82 | OPRM1 (0.42) | SPHK1OPRM1LMNAADH1BADH1C | |
| SCHEMBL6895295 | 0.80 | OPRM1 (0.41) | SPHK1OPRM1LMNAADH1BADH1C | |
| SCHEMBL6892670 | 0.80 | OPRM1 (0.41) | SPHK1OPRM1LMNAADH1BADH1C | |
| SCHEMBL24394272 | 0.79 | OPRM1 (0.44) | SPHK1OPRM1TP53LMNAADH1B | |
| SCHEMBL24409398 | 0.79 | OPRM1 (0.44) | SPHK1OPRM1TP53LMNAADH1B | |
| SCHEMBL20847647 | 0.78 | OPRM1 (0.44) | SPHK1OPRM1TP53S1PR2S1PR1 | |
| SCHEMBL21143019 | 0.78 | DNM1 (0.41) | SPHK1OPRM1S1PR2S1PR1S1PR3 | |
| SCHEMBL18620875 | 0.78 | SPHK1 (0.47) | SPHK1OPRM1TP53CYP2D6LMNA | |
| SCHEMBL19200976 | 0.77 | ADH1B (0.38) | SPHK1OPRM1S1PR2S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0886551-B1 | STABILITY CONTROL AGENT COMPOSITION FOR POLYOLEFIN FOAM | KNAUS DENNIS A (US) | 2004-08-04 | — | — | EP | claimed |