Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4915504 | 0.83 | TRPA1 (0.56) | TSHRALDH1A1HSP90AA1TRPA1AKR1C3 | |
| SCHEMBL6902823 | 0.82 | TRPA1 (0.55) | TSHRALDH1A1HSP90AA1TRPA1AKR1C3 | |
| SCHEMBL4923859 | 0.74 | ADRA2A (0.48) | TSHRALDH1A1MEN1KMT2AADRA2A | |
| SCHEMBL6902848 | 0.73 | ADRA2A (0.44) | TSHRADRA2AADRA1ALMNACYP1A2 | |
| SCHEMBL15330692 | 0.71 | ALDH1A1 (0.50) | TSHRALDH1A1HSP90AA1TRPA1MAPT | |
| SCHEMBL29950657 | 0.71 | ALDH1A1 (0.50) | TSHRALDH1A1HSP90AA1TRPA1MAPT | |
| SCHEMBL5866455 | 0.71 | HSP90AA1 (0.62) | TSHRALDH1A1HSP90AA1TRPA1LMNA | |
| SCHEMBL9672282 | 0.70 | CYP1A2 (0.52) | ALDH1A1MEN1KMT2AADRA2AADRA1A | |
| SCHEMBL30253262 | 0.70 | CYP1A2 (0.52) | ALDH1A1MEN1KMT2AADRA2AADRA1A | |
| SCHEMBL29904615 | 0.69 | TSHR (1.00) | TSHRALDH1A1PBRM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6815481-B2 | FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-11-09 | — | — | US | disclosed |