SCHEMBL6900797

SCHEMBL6900797

CCCCc1ccccc1NS(=O)(=O)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 4/20 0.56
ALDH1A1 P00352 3/20 0.55
TSHR P16473 3/20 0.55
POLB P06746 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.51
KMT2A Q03164 1/20 0.49
RECQL P46063 1/20 0.47
SLC16A3 O15427 1/20 0.45
TP53 P04637 1/20 0.45
THRB P10828 1/20 0.45
IL1RN P18510 1/20 0.44
KEAP1 Q14145 1/20 0.44
ERAP1 Q9NZ08 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10438570 0.90 ALDH1A1 (0.57) METAP2ALDH1A1TSHRPOLBSMN1; SMN2
SCHEMBL27556787 0.88 CA1 (0.54) METAP2ALDH1A1TSHRPOLBSMN1; SMN2
SCHEMBL10272404 0.85 ALDH1A1 (0.71) METAP2ALDH1A1TSHRPOLBSMN1; SMN2
SCHEMBL5470742 0.85 POLB (0.52) METAP2ALDH1A1TSHRPOLBSMN1; SMN2
SCHEMBL3561760 0.83 SLC16A3 (0.63) METAP2ALDH1A1SLC16A3
SCHEMBL3554502 0.82 METAP2 (0.64) METAP2ALDH1A1KMT2ASLC16A3
SCHEMBL7211586 0.81 HTR6 (0.56) ALDH1A1TSHRPOLBSMN1; SMN2KMT2A
SCHEMBL5467224 0.81 DDX3X (0.61) ALDH1A1SMN1; SMN2KMT2ARECQL
SCHEMBL7425678 0.81 ALDH1A1 (0.55) ALDH1A1TSHRKMT2ASLC16A3KEAP1
SCHEMBL3559576 0.80 SLC16A3 (0.69) METAP2ALDH1A1SLC16A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6828375-B2 Containing a thermoplastic elastomer grafted with maleic anhydride, carbon black powder, sulfonamide based material, and alkanedioic acid HYUNDAI MOTOR COMPANY (KR) 2004-12-07 US claimed
US-20020128373-A1 Electroconductive polyamide resin composition and molded product for motor component prepared therefrom HYUNDAI MOTOR COMPANY (KR) 2002-09-12 US claimed
CN-101817767-A Substituted sulphonamide compound and preparation method, medicine composition and application thereof SHANGHAI INST BIOL SCIENCES 2010-09-01 CN disclosed
US-6828375-B2 Containing a thermoplastic elastomer grafted with maleic anhydride, carbon black powder, sulfonamide based material, and alkanedioic acid HYUNDAI MOTOR COMPANY (KR) 2004-12-07 US disclosed
US-20020128373-A1 Electroconductive polyamide resin composition and molded product for motor component prepared therefrom HYUNDAI MOTOR COMPANY (KR) 2002-09-12 US disclosed