Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | TPSAB1 | Q15661 | 5/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SMO | Q99835 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6901826 | 0.83 | KDM4E (0.51) | KDM4ETPSAB1HRH3MEN1KMT2A | |
| SCHEMBL6901614 | 0.81 | TGM2 (0.48) | KDM4ETPSAB1HRH3MEN1KMT2A | |
| SCHEMBL6901323 | 0.79 | MEN1 (0.54) | KDM4EMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL1874105 | 0.77 | PKM (0.73) | KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12685780 | 0.75 | MEN1 (0.85) | TPSAB1HRH3MEN1KMT2ANPSR1 | |
| SCHEMBL4197501 | 0.75 | KDM4E (0.69) | KDM4ETPSAB1HRH3MEN1KMT2A | |
| SCHEMBL5800630 | 0.75 | KDM4E (0.69) | KDM4ETPSAB1HRH3MEN1KMT2A | |
| SCHEMBL14479131 | 0.74 | KDM4E (0.73) | KDM4ETPSAB1HRH3MEN1KMT2A | |
| SCHEMBL5471150 | 0.74 | MEN1 (0.75) | KDM4ETPSAB1HRH3MEN1KMT2A | |
| SCHEMBL6559744 | 0.73 | KDM4E (0.68) | KDM4ETPSAB1HRH3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011060321-A1 | TRANSGLUTAMINASE TG2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | CHDI, INC. (US) | 2011-05-19 | — | — | WO | disclosed |