Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F13A1 | P00488 | 1/20 | 0.53 |
| ▸ | TGM2 | P21980 | 1/20 | 0.53 |
| ▸ | TGM1 | P22735 | 1/20 | 0.53 |
| ▸ | C3AR1 | Q16581 | 13/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1868312 | 0.82 | F13A1 (0.79) | F13A1TGM2TGM1NAMPT | |
| SCHEMBL6902596 | 0.74 | TGM2 (0.68) | F13A1TGM2TGM1 | |
| SCHEMBL6901614 | 0.74 | TGM2 (0.48) | F13A1TGM2TGM1 | |
| SCHEMBL6900590 | 0.73 | TGM2 (0.54) | F13A1TGM2TGM1 | |
| SCHEMBL4378680 | 0.73 | NPC1 (0.62) | C3AR1 | |
| SCHEMBL10305181 | 0.72 | NPC1 (0.67) | C3AR1 | |
| SCHEMBL6899848 | 0.72 | TGM2 (0.62) | F13A1TGM2TGM1 | |
| SCHEMBL1312749 | 0.71 | CHRM1 (0.57) | C3AR1NAMPT | |
| SCHEMBL20353683 | 0.71 | C3AR1 (0.55) | C3AR1 | |
| SCHEMBL6901428 | 0.70 | LMNA (0.48) | F13A1TGM2TGM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011060321-A1 | TRANSGLUTAMINASE TG2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | CHDI, INC. (US) | 2011-05-19 | — | — | WO | disclosed |