Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 8/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 8/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 8/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6901775 | 1.00 | KMT2A (0.36) | KMT2AFAAHGNAI3GNAO1GNAI1 | |
| SCHEMBL3107942 | 0.89 | GNAI3 (0.41) | KMT2AFAAHGNAI3GNAO1GNAI1 | |
| SCHEMBL25420232 | 0.87 | GNAO1 (0.43) | KMT2AFAAHGNAI3GNAO1GNAI1 | |
| SCHEMBL10464788 | 0.87 | GNAO1 (0.43) | KMT2AFAAHGNAI3GNAO1GNAI1 | |
| SCHEMBL25420992 | 0.87 | GNAO1 (0.43) | KMT2AFAAHGNAI3GNAO1GNAI1 | |
| SCHEMBL25253971 | 0.87 | GNAO1 (0.43) | KMT2AFAAHGNAI3GNAO1GNAI1 | |
| SCHEMBL17582303 | 0.87 | KDM4E (0.41) | KMT2AALDH1A1MAPTKDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL7529754 | 0.86 | GNAO1 (0.46) | KMT2AFAAHGNAI3GNAO1GNAI1 | |
| SCHEMBL4073047 | 0.83 | KMT2A (0.41) | KMT2AGNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL7122564 | 0.77 | FAAH (0.48) | FAAHALDH1A1KDM4ECA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6734311-B2 | ANTIINFLAMMATORY AGENTS; ALZHEIMER'S DISEASE; CARDIOVASCULAR DISORDERS | MERCK & CO., INC. | 2004-05-11 | — | — | US | disclosed |
| US-20030092746-A1 | Substituted amidine derivatives as inhibitors of cell adhesion | MERCK & CO., INC. | 2003-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092746-A1 | Substituted amidine derivatives as inhibitors of cell adhesion | VCAM1, CD4, ICAM1 | KMT2A 1961/4885FAAH 795/4885GNAI3 2785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.