SCHEMBL4073047

SCHEMBL4073047

CCCCS(=O)(=O)N1CCNCC1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
KDM4E B2RXH2 1/20 0.41
NPC1 O15118 1/20 0.38
GNAI3 P08754 8/20 0.38
GNAO1 P09471 8/20 0.38
GNAI1 P63096 8/20 0.38
L3MBTL1 Q9Y468 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
EPHX2 P34913 1/20 0.35
HDAC1 Q13547 1/20 0.35
GAA P10253 1/20 0.34
PKM P14618 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3107942 0.94 GNAI3 (0.41) KMT2AALDH1A1MAPTKDM4EGNAI3
SCHEMBL25253971 0.92 GNAO1 (0.43) KMT2AALDH1A1MAPTKDM4EGNAI3
SCHEMBL25420992 0.92 GNAO1 (0.43) KMT2AALDH1A1MAPTKDM4EGNAI3
SCHEMBL25420232 0.92 GNAO1 (0.43) KMT2AALDH1A1MAPTKDM4EGNAI3
SCHEMBL10464788 0.92 GNAO1 (0.43) KMT2AALDH1A1MAPTKDM4EGNAI3
Hydrochloric Acid SCHEMBL7529754 0.91 GNAO1 (0.46) KMT2AKDM4EGNAI3GNAO1GNAI1
SCHEMBL190917 0.88 L3MBTL1 (0.45) KMT2AALDH1A1MAPTKDM4ENPC1
SCHEMBL31711454 0.86 L3MBTL1 (0.44) KMT2AALDH1A1MAPTKDM4ENPC1
Hydrochloric Acid SCHEMBL999877 0.86 L3MBTL1 (0.44) KMT2AALDH1A1MAPTKDM4ENPC1
SCHEMBL734812 0.85 L3MBTL1 (0.44) ALDH1A1MAPTKDM4ENPC1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260132111-A1 Host-Targeted Pan-Respiratory Antiviral Small Molecule Therapeutics PROSETTA BIOSCIENCES INC (US) 2026-05-14 US disclosed
US-12459901-B2 Host-targeted pan-respiratory antiviral small molecule therapeutics PROSETTA BIOSCIENCES, INC. (US) 2025-11-04 US disclosed
EP-4441137-A1 MELT ADDITIVES FOR LOW SURFACE-ENERGY APPLICATIONS 3M Innovative Properties Company (US) 2024-10-09 EP disclosed
EP-4402124-A1 NOVEL HOST-TARGETED PAN-RESPIRATORY ANTIVIRAL SMALL MOLECULE THERAPEUTICS Prosetta Biosciences, Inc. (US) 2024-07-24 EP disclosed
US-12017997-B2 Host-targeted pan-respiratory antiviral small molecule therapeutics PROSETTA BIOSCIENCES, INC. (US) 2024-06-25 US disclosed
US-20240190826-A1 Novel Host-Targeted Pan-Respiratory Antiviral Small Molecule Therapeutics PROSETTA BIOSCIENCES, INC. 2024-06-13 US disclosed
WO-2023099977-A1 MELT ADDITIVES FOR LOW SURFACE-ENERGY APPLICATIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-06-08 WO disclosed
US-20230147603-A1 HOST-TARGETED PAN-RESPIRATORY ANTIVIRAL SMALL MOLECULE THERAPEUTICS PROSETTA BIOSCIENCES, INC. 2023-05-11 US disclosed
WO-2023069770-A1 NOVEL HOST-TARGETED PAN-RESPIRATORY ANTIVIRAL SMALL MOLECULE THERAPEUTICS PROSETTA BIOSCIENCES, INC. (US) 2023-04-27 WO disclosed
US-8883781-B2 Thienopyrimidines useful as modulators of ion channels VERTEX PHARMACEUTICALS INCORPORATED (US) 2014-11-11 US disclosed
CN-101500575-A Thienopyrimidines useful as modulators of ion channels VERTEX PHARMA (US) 2009-08-05 CN disclosed
EP-2043654-A2 THIENOPYRIMIDINES USEFUL AS MODULATORS OF ION CHANNELS Vertex Pharmaceuticals, Inc. (US) 2009-04-08 EP disclosed
WO-2007146284-A2 THIENOPYRIMIDINES USEFUL AS MODULATORS OF ION CHANNELS VERTEX PHARMACEUTICALS INCORPORATED (US) 2007-12-21 WO disclosed
US-20070287717-A1 Thienopyrimidines useful as modulators of ion channels VERTEX PHARMACEUTICALS INCORPORATED 2007-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132111-A1 Host-Targeted Pan-Respiratory Antiviral Small Molecule Therapeutics NCOR1, HAVCR2, NR3C1 KMT2A 4124/4885ALDH1A1 3991/4885MAPT 3761/4885
US-12017997-B2 Host-targeted pan-respiratory antiviral small molecule therapeutics MAVS, SARS1, ZC3HAV1 KMT2A 4108/4885ALDH1A1 4359/4885MAPT 3295/4885
US-20240190826-A1 Novel Host-Targeted Pan-Respiratory Antiviral Small Molecule Therapeutics MAVS, SARS1, ZC3HAV1 KMT2A 3926/4885ALDH1A1 4452/4885MAPT 3145/4885
US-20070287717-A1 Thienopyrimidines useful as modulators of ion channels KCNJ1, KCNJ2, TRPV1 KMT2A 2787/4885ALDH1A1 1670/4885MAPT 2226/4885
US-12459901-B2 Host-targeted pan-respiratory antiviral small molecule therapeutics MAVS, SARS1, ZC3HAV1 KMT2A 4108/4885ALDH1A1 4359/4885MAPT 3295/4885
US-20230147603-A1 HOST-TARGETED PAN-RESPIRATORY ANTIVIRAL SMALL MOLECULE THERAPEUTICS MAVS, SARS1, ZC3HAV1 KMT2A 4108/4885ALDH1A1 4359/4885MAPT 3295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.