SCHEMBL69018

SCHEMBL69018

Oc1ccc(F)cc1Sc1cc(F)ccc1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.54
HPGD P15428 4/20 0.54
KMT2A Q03164 4/20 0.54
HSD17B10 Q99714 4/20 0.54
ALOX15 P16050 3/20 0.54
LMNA P02545 3/20 0.54
ALDH1A1 P00352 3/20 0.54
TP53 P04637 2/20 0.54
MAPT P10636 2/20 0.54
ALOX12 P18054 2/20 0.54
HTT P42858 2/20 0.54
HIF1A Q16665 2/20 0.54
GAA P10253 1/20 0.54
PLA2G1B P04054 1/20 0.54
HSP90AA1 P07900 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2D6 P10635 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
ATG4B Q9Y4P1 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3847009 0.81 MEN1 (0.45) MEN1HPGDKMT2AHSD17B10ALOX15
SCHEMBL8419009 0.74 HSD17B10 (0.58) MEN1HPGDKMT2AHSD17B10ALOX15
SCHEMBL7269852 0.74 CA3 (0.46) ALDH1A1PLA2G1BATG4BCA3CA6
SCHEMBL13652191 0.73 PTGS2 (0.39) MEN1HPGDKMT2AHSD17B10ALOX15
SCHEMBL29392814 0.73
SCHEMBL69524 0.73
SCHEMBL101785 0.72
SCHEMBL13647657 0.71 DAO (0.47) KMT2AHSD17B10LMNAALDH1A1MAPT
SCHEMBL25433140 0.70 CA6 (0.62) MAPTCA3CA6CA5ACA9
SCHEMBL185204 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
EP-0457334-B1 Carbonates of acetylenic alcohols NIPPON PAINT CO LTD (JP) 1994-08-10 EP disclosed
US-5258542-A Carbonates of acetylenic alcohols NIPPON PAINT CO., LTD. (JP) 1993-11-02 US disclosed
US-5194653-A Useful in making heat resistant liquid crystalline polymers NIPPON PAINT COMPANY, LIMITED (JP) 1993-03-16 US disclosed
EP-0457334-A1 Carbonates of acetylenic alcohols NIPPON PAINT CO., LTD. (JP) 1991-11-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 MEN1 4831/4885HPGD 3275/4885KMT2A 1042/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.