Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5582943 | 0.91 | ACHE (0.58) | PKMLMNAACHEELANECYP3A4 | |
| SCHEMBL14700515 | 0.84 | BACE1 (0.51) | LMNAACHECYP3A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL27904636 | 0.84 | PKM (0.46) | PPARGPPARAPKMLMNAACHE | |
| SCHEMBL19084240 | 0.82 | BACE1 (0.56) | LMNAACHEELANECYP3A4MAPT | |
| SCHEMBL1551128 | 0.81 | LMNA (0.55) | PPARGPPARAPKMLMNAELANE | |
| SCHEMBL4198689 | 0.81 | LMNA (0.55) | PKMLMNAACHEMAPTALDH1A1 | |
| SCHEMBL19685841 | 0.81 | CYP3A4 (0.46) | PKMLMNAACHEELANECYP3A4 | |
| SCHEMBL180340 | 0.79 | PPARG (0.47) | PPARGPPARAPKMACHEELANE | |
| SCHEMBL862851 | 0.77 | ACHE (0.65) | PKMLMNAACHECYP3A4MAPT | |
| SCHEMBL15085173 | 0.77 | MAPT (0.62) | LMNAELANECYP3A4MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011034828-A1 | SUBSTITUTED PARA-BIPHENYLOXYMETHYL DIHYDRO OXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF | SANOFI-AVENTIS (FR) | 2011-03-24 | — | — | WO | disclosed |