SCHEMBL19685841

SCHEMBL19685841

CC(=O)Oc1ccc(C)c(-c2cc(O)cc(-c3ccccc3C)c2C)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.46
PKM P14618 1/20 0.46
ACHE P22303 1/20 0.46
BACE1 P56817 3/20 0.45
MAPT P10636 5/20 0.43
ALDH1A1 P00352 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
LMNA P02545 3/20 0.43
MAPK1 P28482 1/20 0.40
ELANE P08246 1/20 0.40
NPC1 O15118 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
CASP3 P42574 1/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
SENP6 Q9GZR1 1/20 0.39
FFAR1 O14842 1/20 0.39
FFAR4 Q5NUL3 1/20 0.39
KDM4E B2RXH2 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL180340 0.81 PPARG (0.47) PKMACHEBACE1MAPTALDH1A1
SCHEMBL6901954 0.81 PPARG (0.54) CYP3A4PKMACHEBACE1MAPT
SCHEMBL7033583 0.77 HTR7 (0.49) PKMACHEBACE1MAPTALDH1A1
SCHEMBL5682633 0.73 ACHE (0.61) CYP3A4PKMACHEMAPTALDH1A1
SCHEMBL19084240 0.73 BACE1 (0.56) CYP3A4ACHEBACE1MAPTALDH1A1
SCHEMBL1551128 0.72 LMNA (0.55) PKMBACE1MAPTALDH1A1LMNA
SCHEMBL27904636 0.72 PKM (0.46) CYP3A4PKMACHEBACE1MAPT
SCHEMBL5582943 0.71 ACHE (0.58) CYP3A4PKMACHEMAPTALDH1A1
SCHEMBL22480245 0.71 HSD17B10 (0.51) PKMACHEMAPTALDH1A1SMN1; SMN2
SCHEMBL21899871 0.71 PPARG (0.44) PKMACHEBACE1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170351178-A1 COMPOSITION FOR FORMING ORGANIC ANTI-REFLECTIVE COATING LAYER SUITABLE FOR NEGATIVE TONE DEVELOPMENT DONGJIN SEMICHEM CO., LTD. (KR) 2017-12-07 US disclosed