Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F13A1 | P00488 | 19/20 | 0.52 |
| ▸ | TGM2 | P21980 | 19/20 | 0.52 |
| ▸ | TGM1 | P22735 | 19/20 | 0.52 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1870168 | 0.84 | F13A1 (0.75) | F13A1TGM2TGM1TGM3 | |
| SCHEMBL6901811 | 0.83 | F13A1 (0.72) | F13A1TGM2TGM1TGM3 | |
| SCHEMBL6902596 | 0.81 | TGM2 (0.68) | F13A1TGM2TGM1TGM3 | |
| SCHEMBL6902507 | 0.75 | TGM2 (0.65) | F13A1TGM2TGM1TGM3 | |
| SCHEMBL11889747 | 0.72 | NPC1 (0.52) | — | |
| SCHEMBL6901428 | 0.71 | LMNA (0.48) | F13A1TGM2TGM1TGM3 | |
| SCHEMBL6899848 | 0.70 | TGM2 (0.62) | F13A1TGM2TGM1TGM3 | |
| SCHEMBL7596038 | 0.69 | ABCB1 (0.46) | — | |
| SCHEMBL6901614 | 0.69 | TGM2 (0.48) | F13A1TGM2TGM1 | |
| SCHEMBL1873828 | 0.69 | F13A1 (1.00) | F13A1TGM2TGM1TGM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011060321-A1 | TRANSGLUTAMINASE TG2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | CHDI, INC. (US) | 2011-05-19 | — | — | WO | disclosed |