SCHEMBL690271

SCHEMBL690271

Fc1cc(F)c(B(c2c(F)cc(F)cc2F)c2c(F)cc(F)cc2F)c(F)c1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 1/20 0.37
RAPGEF4 Q8WZA2 1/20 0.36
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
ALDH1A1 P00352 2/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA9 Q16790 1/20 0.33
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
PKM P14618 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
TGM2 P21980 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7721835 0.89 CES2 (0.34) ERN1RAPGEF4CES2CES1
SCHEMBL26770173 0.87 NFE2L2 (0.34) ERN1RAPGEF4CES2CES1ALDH1A1
SCHEMBL30593708 0.81 CES2 (0.30) CES2CES1
SCHEMBL29229458 0.78 ERN1 (0.36) ERN1RAPGEF4CES2CES1ALDH1A1
SCHEMBL29229473 0.78 ERN1 (0.36) ERN1RAPGEF4CES2CES1ALDH1A1
SCHEMBL1265371 0.77 CYP1A2 (0.34) ALDH1A1RAB9A
SCHEMBL4882783 0.75 LMNA (0.32) RAPGEF4ALDH1A1MEN1MAPTRAB9A
SCHEMBL30464887 0.75 LMNA (0.32) RAPGEF4ALDH1A1MEN1MAPTRAB9A
SCHEMBL6874364 0.75 ERN1 (0.39) ERN1CES2CES1ALDH1A1CA12
SCHEMBL1359177 0.75 ERN1 (0.39) ERN1CES2CES1ALDH1A1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 708 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119930880-A Polyethylene rich in serial crystal structure and preparation method and application thereof 浙江大学 2025-05-06 CN claimed
CN-119874465-A New method for synthesizing fluoroalkyl substituted 4,4' -diaminodiphenyl methane compound 海南大学 2025-04-25 CN claimed
CN-116656036-B High-toughness polyolefin film and preparation method thereof 浙江大学宁波“五位一体”校区教育发展中心 2025-04-04 CN claimed
CN-116987220-B High-strength high-toughness high-hardness polyolefin and application thereof 浙江大学 2025-04-04 CN claimed
CN-115991721-B Phosphine-containing compound, preparation method thereof and application of phosphine-containing compound as ligand of ethylene oligomerization catalyst composition 中化学科学技术研究有限公司 2025-02-18 CN claimed
CN-119192715-A Wide-distribution easy-processing polyethylene and application thereof 浙江大学 2024-12-27 CN claimed
CN-119192714-A Easily-processed high-impact polyethylene and preparation method and application thereof 浙江大学 2024-12-27 CN claimed
CN-118496453-A Covalent organic framework material functionalized by hindered Lewis acid-base pairs, preparation method and application 天津大学 2024-08-16 CN claimed
CN-112745366-B Silicon-based bridged metallocene compound, and preparation method and application thereof 中国石油化工股份有限公司 2024-05-24 CN claimed
CN-117756842-A Shan Maomao metal catalyst, and preparation method and application thereof 国家能源集团宁夏煤业有限责任公司 2024-03-26 CN claimed
US-7169864-B2 Loeading and heating a catalyst support with an alumoxane and further loading with a Group IVB metallocene and a second aluminoxane cocatalyst alone or in combination with a Lewis Acid or ionic compound; improved catalyst selectivity and polymerization efficiency NOVOLEN TECHNOLOGY HOLDINGS, C.V. (NL) 2007-01-30 US claimed
EP-1740622-A2 METALLOCENE LIGANDS, METALLOCENE COMPOUNDS AND METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS Novolen Technology Holdings C.V. (NL) 2007-01-10 EP claimed
WO-2006060544-A1 METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) 2006-06-08 WO claimed
EP-1358142-B1 PROCESS FOR ALKOXYLATION WITH A BORON-CONTAINING CATALYST RHODIA (US) 2006-06-07 EP claimed
US-20060116490-A1 Metallocene catalysts, their synthesis and their use for the polymerization of olefins LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) 2006-06-01 US claimed
WO-2005105863-A2 METALLOCENE LIGANDS, METALLOCENE COMPOUNDS AND METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) 2005-11-10 WO claimed
US-20050239979-A1 Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) 2005-10-27 US claimed
EP-1358142-A1 PROCESS FOR ALKOXYLATION WITH A BORON-CONTAINING CATALYST Rhodia, Inc. (US) 2003-11-05 EP claimed
US-20020128521-A1 Process for alkoxylation with a boron-containing catalyst RHODIA OPERATIONS (FR) 2002-09-12 US claimed
WO-2002057209-A1 PROCESS FOR ALKOXYLATION WITH A BORON-CONTAINING CATALYST RHODIA, INC. (US) 2002-07-25 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020128521-A1 Process for alkoxylation with a boron-containing catalyst ALKBH3, AOX1, FOXO3 ERN1 3142/4885RAPGEF4 3878/4885CES2 1432/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.