Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.74 |
| ▸ | HPGD | P15428 | 7/20 | 0.74 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.74 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.74 |
| ▸ | THRB | P10828 | 1/20 | 0.74 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 5/20 | 0.56 |
| ▸ | CASP1 | P29466 | 5/20 | 0.56 |
| ▸ | CASP7 | P55210 | 5/20 | 0.56 |
| ▸ | CA9 | Q16790 | 4/20 | 0.56 |
| ▸ | GLA | P06280 | 3/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Methylesculetin SCHEMBL409482 | 0.85 | MCL1 (1.00) | ALDH1A1HSD17B10KDM4EHPGDMCL1 | |
| SCHEMBL30450241 | 0.85 | KDM4E (0.62) | ALDH1A1HSD17B10KDM4EHPGDMCL1 | |
| SCHEMBL29061776 | 0.85 | KDM4E (0.62) | ALDH1A1HSD17B10KDM4EHPGDMCL1 | |
| 4-Methylesculetin SCHEMBL29361762 | 0.85 | MCL1 (1.00) | ALDH1A1HSD17B10KDM4EHPGDMCL1 | |
| SCHEMBL24865598 | 0.84 | ALDH1A1 (0.82) | ALDH1A1HSD17B10KDM4EHPGDMCL1 | |
| 4-Methylesculetin SCHEMBL27453331 | 0.84 | ALDH1A1 (0.96) | ALDH1A1HSD17B10KDM4EHPGDMCL1 | |
| 4-Methylesculetin SCHEMBL6839210 | 0.84 | MCL1 (0.96) | ALDH1A1HSD17B10KDM4EHPGDMCL1 | |
| SCHEMBL31736933 | 0.84 | KDM4E (0.61) | ALDH1A1HSD17B10KDM4EHPGDMCL1 | |
| SCHEMBL11235774 | 0.80 | KDM4E (0.61) | ALDH1A1HSD17B10KDM4EHPGDMCL1 | |
| SCHEMBL31357189 | 0.79 | MCL1 (1.00) | ALDH1A1HSD17B10KDM4EHPGDMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083889-B | Yi Lei oxazoles and application of the coumarin derivative in terms of pesticide | 青岛农业大学 | 2018-07-06 | — | — | CN | disclosed |
| CN-106083889-A | One class azoles coumarin derivative application in terms of pesticide | 青岛农业大学 | 2016-11-09 | — | — | CN | disclosed |
| US-20040053893-A1 | Method of assaying iysophospholipase d activity | AZWELL INC. (JP) | 2004-03-18 | — | — | US | disclosed |
| EP-1357126-A1 | METHOD OF ASSAYING LYSOPHOSPHOLIPASE D ACTIVITY | Azwell Inc. (JP) | 2003-10-29 | — | — | EP | disclosed |
| CN-1117035-C | Water treatment agent | NIPPON CATALYTIC CHEM IND (JP) | 2003-08-06 | — | — | CN | disclosed |
| EP-0761604-B1 | An agent for water treatment | NIPPON CATALYTIC CHEM IND (JP) | 2000-06-14 | — | — | EP | disclosed |
| US-5948268-A | DISSOLVING IN WATER TO BE TREATED A POLYMER FORMED FROM WATER SOLUBLE MONOMER UNITS COMPRISING A (POLY)ALKYLENE OXIDE END CAPPED WITH AN ADDITION POLYMERIZABLE GROUP AT ONE END AND AN INTENSELY FLUORESCENT GROUP AT OTHER | NIPPON SHOKUBAI CO., LTD. (JP) | 1999-09-07 | — | — | US | disclosed |
| CN-1151380-A | Water treatment agent | NIPPON CATALYTIC CHEM IND (JP) | 1997-06-11 | — | — | CN | disclosed |
| EP-0761604-A2 | An agent for water treatment | NIPPON SHOKUBAI CO., LTD. (JP) | 1997-03-12 | — | — | EP | disclosed |
| EP-0485882-A1 | A polymer utilized in water system and a method of treatment of water system | KURITA WATER INDUSTRIES LTD. (JP) | 1992-05-20 | — | — | EP | disclosed |
| US-5011964-A | Phospholipase cleavage of water-insoluble ester yields chromogen for colorimetric analysis | CORNELL RESEARCH FOUNDATION, INC. (US) | 1991-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053893-A1 | Method of assaying iysophospholipase d activity | LYPLA1, LPL, LYPLA2 | ALDH1A1 717/4885HSD17B10 242/4885KDM4E 3867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.