Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | AGER | Q15109 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6905912 | 0.77 | LMNA (0.32) | HSP90AA1HSP90B1DGAT1KDM4EALDH1A1 | |
| SCHEMBL6905906 | 0.77 | LMNA (0.32) | HSP90AA1HSP90B1DGAT1KDM4EALDH1A1 | |
| SCHEMBL6905827 | 0.75 | GAA (0.41) | DGAT1ALDH1A1 | |
| SCHEMBL2983095 | 0.72 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL9592717 | 0.72 | KCNH2 (0.37) | DGAT1ALDH1A1 | |
| SCHEMBL3946290 | 0.71 | HSP90AA1 (0.31) | HSP90AA1HSP90B1 | |
| SCHEMBL2647731 | 0.71 | DGAT1 (0.36) | DGAT1ALDH1A1 | |
| SCHEMBL3070906 | 0.71 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL9026376 | 0.70 | AGTR1 (0.40) | DGAT1ALDH1A1CYP19A1 | |
| SCHEMBL5879334 | 0.70 | MAPT (0.40) | DGAT1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110764-A1 | Inhibitors of prenyl-protein transferase | STUMP CRAIG A (US) | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110764-A1 | Inhibitors of prenyl-protein transferase | FNTA, KRAS, PTAR1 | HSP90AA1 2146/4885HSP90B1 441/4885DGAT1 334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.